Virginia Kaklamani, MD, DSc
Articles by Virginia Kaklamani, MD, DSc

26 Subgroup Analysis of Patients With No Prior Chemotherapy in EMERALD: A Phase 3 Trial Evaluating Elacestrant, an Oral Selective Estrogen Receptor Degrader (SERD), Vs Investigator’s Choice of Endocrine Monotherapy for ER+/HER2– Advanced/ Metastatic Breast Cancer (mBC)
ByVirginia Kaklamani, MD, DSc,Aditya Bardia, MD, MPH, FASCO,Phillippe Aftimos,Javier Cortes,Patrick Neven, MD, PhD,Alberto J. Montero, MD, MBA, CPHQ,Joo Hyuk Sohn,Giulia Tonini,Krzysztof J. Grzegorzewski,François-Clément Bidard 
Future Perspectives in HER2+ mBC
ByJoyce O’Shaughnessy, MD,Virginia Kaklamani, MD, DSc,Heather McArthur, MD, MPH,Andrew Brenner, MD, PhD The panel closes their discussion by musing on the future of HER2 mBC treatments.

Leptomeningeal Metastases in HER2+ mBC
ByJoyce O’Shaughnessy, MD,Virginia Kaklamani, MD, DSc,Heather McArthur, MD, MPH,Andrew Brenner, MD, PhD A discussion on the prevalence and treatment difficulties of leptomeningeal metastases in HER2+ mBC.

Systemic Therapy Before Whole Brain Radiation for HER2+ mBC with Brain Metastases
ByJoyce O’Shaughnessy, MD,Virginia Kaklamani, MD, DSc,Heather McArthur, MD, MPH,Andrew Brenner, MD, PhD The panel discusses the systemic therapy options for patients with HER2+ mBC with brain metastases before moving to whole brain radiation therapy.

Case Presentation: A 62-Year-Old Woman with HER2+ mBC with Pulmonary and Brain Metastases
ByJoyce O’Shaughnessy, MD,Virginia Kaklamani, MD, DSc,Heather McArthur, MD, MPH,Andrew Brenner, MD, PhD Andrew Brenner, MD, presents the case of a 62-year-old patient with stage II HER2+ mBC presenting with both pulmonary and brain metastases.

Managing Adverse Events of Tucatinib in Patients with HER2+ mBC with Brain Metastases
ByJoyce O’Shaughnessy, MD,Virginia Kaklamani, MD, DSc,Heather McArthur, MD, MPH,Andrew Brenner, MD, PhD Joyce O’Shaughnessy, MD, starts a conversation on managing the adverse events of tucatinib therapy in patients with HER2+ mBC with brain metastases.

Treatment Approaches in HER2+ mBC with Brain Metastases
ByJoyce O’Shaughnessy, MD,Virginia Kaklamani, MD, DSc,Heather McArthur, MD, MPH,Andrew Brenner, MD, PhD The panel reviews the treatment approaches for HER2+ mBC with active brain metastases and the factors to consider during treatment decision-making.

Case Presentation: A 60-Year-Old Woman with HER2+ mBC with Brain Metastases
ByJoyce O’Shaughnessy, MD,Virginia Kaklamani, MD, DSc,Heather McArthur, MD, MPH,Andrew Brenner, MD, PhD Virginia Kaklamani, MD, presents the case of a 60-year-old patient with stage III HER2+ mBC with brain metastases.

Third-Line Treatment Options for HER2+ mBC after Progression on Trastuzumab Deruxtecan
ByJoyce O’Shaughnessy, MD,Virginia Kaklamani, MD, DSc,Heather McArthur, MD, MPH,Andrew Brenner, MD, PhD Heather McArthur, MD, describes what treatment options she would consider in the third-line setting for HER2+ mBC.

Screening for Brain Metastases in HER2+ Breast Cancer
ByJoyce O’Shaughnessy, MD,Virginia Kaklamani, MD, DSc,Heather McArthur, MD, MPH,Andrew Brenner, MD, PhD Andrew Brenner, MD, explains when physicians should screen patients with HER2+ breast cancer for brain metastases.

Trastuzumab Deruxtecan Maintenance after First-Line Therapy for HER2+ mBC
ByJoyce O’Shaughnessy, MD,Virginia Kaklamani, MD, DSc,Heather McArthur, MD, MPH,Andrew Brenner, MD, PhD Joyce O’Shaughnessy, MD, starts a discussion on maintenance therapy with trastuzumab deruxtecan in patient with HER2+ mBC.

Case Presentation: A 69-Year-Old Woman with HER2+ Metastatic Breast Cancer (mBC)
ByJoyce O’Shaughnessy, MD,Virginia Kaklamani, MD, DSc,Heather McArthur, MD, MPH,Andrew Brenner, MD, PhD Heather McArthur, MD, presents the case of a 69-year-old woman with stage II HER2+ mBC for discussion.

Advice for community physicians treating HER2+ breast cancer.

Dr. Virginia Kaklamani discusses the role of maintenance therapies for HER2+ breast cancer.

Virginia Kaklamani, MD, DSc, provides an overview of the goals of care for HER2+ breast cancer.

A review of the currently available frontline treatment options for HER2+ breast cancer.

Virginia Kaklamani, MD, DSc, provides an overview of the goals of care for HER2+ breast cancer.