For many individuals, keloids present a symptomatic and cosmetic issue after tissue injury. Surgical excision followed by immediate adjuvant RT provides excellent local control and cosmesis with minimal toxicity. Treatment with both prescribed regimens yielded equal results.
A hypofractionated course of 8 Gy/1 fx radiation therapy in the treatment of bony multiple myeloma metastases is an efficient and effective way to reduce pain and reduce the time from the completion of radiation therapy to the start of chemotherapy in patients with multiple myeloma.
Systemic inflammatory markers are independent prognostic factors for survival in oropharyngeal cancer patients treated with radiation therapy. Future investigations to validate the identified cut points and to develop risk-adaptive treatment strategies are needed.
Assuming IMRT became more prevalent from 2000 to 2002, the annual incidence rate of second malignancy remains consistently below that of patients who receive no radiation. This pattern contradicts the argument that IMRT significantly increases the risk for second malignancy.
Differences in the legal needs of economically and geographically diverse patients with cancer suggest that those needs are not determined solely by disease state but that they also correspond with geographic and economic characteristics.
Forming a successful quality improvement project is challenging at times but ultimately provides an excellent educational experience for residents and a rewarding opportunity to help patients.
From our institutional experience, low-dose RT in addition to docetaxel and cetuximab is well tolerated. More durable treatment options may exist for definitive treatment; however, this protocol may offer low-morbidity palliation in select patients.
Increasing time from diagnosis to simulation and from simulation until the start of therapy is associated with worse outcomes. Patients with HPV-associated oropharyngeal squamous cell carcinoma are at increased risk of nodal progression before treatment.
Rates of clinically significant GI and GU toxicities are modest following SBRT plus IMRT. Placement of rectal spacers may decrease rectal toxicity. Future studies should also identify dosimetric predictors of these toxicities.