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WASHINGTON-Who says advertising doesn’t work? A new study finds that three heavily advertised brands of cigarettes-Marlboro, Newport, and Camel-are the most popular with American teen-agers. Indeed, 88% of high school seniors who smoke use one of the three. They are also the choice of 86% of 10th graders and 82% of 8th graders.

PHILADELPHIA-The combination of a common cholesterol-lowering agent, lovastatin (Mevacor), with an NSAID may be more effective than NSAIDs alone in the chemoprevention of colon cancer, a new study shows. The data were presented at the American Association for Cancer Research meeting.

ASCO-For colorectal cancer patients who have undergone surgery for liver metastases, adjuvant therapy that combines hepatic arterial chemotherapy and systemic chemotherapy effectively controls local disease and significantly increases 2-year survival, Nancy Kemeny, MD, of Memorial Sloan-Kettering Cancer Center, reported at ASCO.

ORLANDO-The most important aspects in treating locally advanced breast cancer are thorough preoperative chemotherapy and a treatment team that combines chemotherapy, surgery, and radiation, two experts said at a special session of the Society of Surgical Oncology’s Annual Cancer Symposium. The presenters were Frederick C. Ames, MD, of the University of Texas M.D. Anderson Cancer Center, and A. Marilyn Leitch, MD, of the University of Texas Southwestern Medical Center, Dallas.

ATLANTA–Human immunodeficiency virus (HIV) infection is one of the leading causes of morbidity and mortality in the United States. Testing for HIV, in conjunction with counseling and other preventive services, can reduce the risk for HIV infection and appropriately link infected persons to treatment. To characterize HIV testing by region, state, and sex, the Centers for Disease Control (CDC) analyzed data from the 1996 Behavioral Risk Factor Surveillance System (BRFSS). This report summarizes the results of that analysis, which indicate a high degree of variability in HIV testing throughout the United States.

BETHESDA, Md-Nine children’s cancer centers have joined together under the auspices of the National Cancer Institute (NCI) to form the Pediatric Brain Tumor Consortium. The NCI will provide the group $2 million a year for 5 years to fund collaborative efforts to develop and carry out pilot studies and early clinical trials of promising new therapies for children with brain malignancies.

ALEXANDRIA, Va-As cancer care increasingly shifts from inpatient to outpatient services and consumers use the Internet to educate themselves about their disease and their options, cancer programs must concentrate more carefully on marketing themselves as the answer to potential patients’ needs, said Patti Jamieson, MSSW, MBA, service line administrator for oncology, University of Illinois at Chicago Medical Center.

FORT LAUDERDALE, Fla-Time is running out for lobbying against the Health Care Finance Administration’s (HCFA) proposed Medicare hospital outpatient fee schedules, based on ambulatory payment classifications (APCs). The deadline for comments is June 30, 1999.

The article by Champlin and colleagues summarizes exciting recent clinical results in allogeneic bone marrow transplantation (BMT) for leukemia and lymphoma achieved by “reengineering” the process to take maximum advantage of the powerful

ORLANDO-Ten-year survival results from a major intergroup study support the use of elective (immediate) regional lymph node dissection (ELND) rather than watchful waiting for patients with intermediate-thickness melanomas (1 to 4 mm).

ALEXANDRIA, Va-“Organized opposition to the Health Care Finance Administration’s (HCFA) proposal to reimburse outpatient Medicare cancer services according to ambulatory payment classifications (APCs) now includes many of the major players in the oncology community,” reported Lee E. Mortenson, DPA, executive director of the Association of Community Cancer Centers (ACCC), Rockville, Maryland.

SAN FRANCISCO-Although there are many good metaanalyses, derived from combining the results of numerous solid clinical trials, there are also many “filled with garbage,” Deborah Grady, MD, said at the Seventh Symposium on Clinical Trials: Design, Methods and Controversies. It is incumbent on the physician to be able to distinguish the good from the bad, said Dr. Grady, associate professor of epidemiology, biostatistics and medicine, University of California, San Francisco (UCSF).

COLUMBUS, Ohio-Hearing the words, “You have cancer,” is immediately upsetting. “That distress can echo through the years, negatively affecting a person’s quality of life [QOL] long after the initial diagnosis of cancer,” said Betty R. Ferrell, PhD, RN, research scientist, City of Hope National Medical Center. She spoke at a conference on cancer survi-vorship sponsored by the James Cancer Hospital and Solove Research Institute at Ohio State University. Indeed, she said, in a survey of cancer survivors, distress over initial diagnosis was ranked as the single most negative influence on quality of life, worse than fear of recurrent cancer, fear of cancer spreading, or physical symptoms like fatigue.

ALEXANDRIA, Va-Treating a patient in a clinical trial-nearly always a cancer patient’s best treatment option-is no more costly and far more effective than giving supposedly less expensive “established” care, reported William P.Peters, MD, PhD, president, director, and chief executive officer of the Barbara Ann Karmanos Cancer Institute, Detroit. Dr. Peters discussed a series of cost and outcome studies that reached this conclusion at the Annual Meeting of the Association of Community Cancer Centers.

MIAMI BEACH, Fla-The development of chemotherapy agents peaked between 1985 and 1990, Dr. Eric Rowinsky said at the annual meeting of the Network of Oncology Communication and Research (NOCR). “However, we saw the same types of drugs being developed (analogs of the platinums and anthracyclines) because we were using the same old screening system,” he said.

ALEXANDRIA, Va-Although physicians and other health professionals are not taught how to create or pass legislation, it is vital “for each of us to be involved in the legislative process,” Edward L. Braud, MD, said at the 25th Annual Meeting of the Association of Community Cancer Centers (ACCC).

ALEXANDRIA, Virginia-Genetic alterations very early in the disease process lie at the root of every cancer. Functional genomics, the study of which genes are actually functioning at a given time or stage, affords a “new approach” to fighting cancer, reported Kristina Cole, MD, PhD, a cancer research training fellow at the National Cancer Institute, Bethesda, Maryland.

ALEXANDRIA, Va-With 56% of cancer patients now receiving off-label therapies and “more than 50%” of physicians reporting problems getting reimbursement for these treatments, assuring coverage for such medications is a major focus of the Association of Community Cancer Centers’ legislative efforts at the state level, said Christian Downs, MHA, director of Provider Economics and Public Policy for the ACCC.

ALEXANDRIA, Va-Although nurses traditionally have not been sued individually for malpractice, changes in technology, medical practice, and medical economics have made them increasingly vulnerable to being named in litigation, according to Susan B. Fink, RN, JD, an attorney with Koskoff, Koskoff & Bieder, PC, of Bridgeport, Conn.

COLUMBUS, Ohio-Many aspects of cancer patient care can be improved or enhanced with the use of music therapy, said Deforia Lane, PhD, resident director of music therapy, University Hospitals of Cleveland-Ireland Cancer Center/Rainbow Babies & Children’s Hospital, and assistant clinical professor of medicine, Case Western Reserve University. Dr. Lane, a board-certified music therapist, spoke at a conference on cancer survivorship sponsored by the Ohio State University’s James Cancer Center and Solove Research Institute.

ORLANDO-The new frontiers in colorectal cancer include multimodality treatment used preoperatively and a new group of oral fluoropyramidine drugs, according to presentations at the Society of Surgical Oncology’s 52nd Annual Cancer Symposium.