
T-DXd and Dato-DXd are now approved treatments in Japan for patients with breast cancer.
A 54-year-old man presents with chest pain, cough, shortness of breath, and a mediastinal mass. What is your diagnosis?
A 54-year-old man presents with symptoms of chest pain, cough, and shortness of breath. Diagnostic imaging reveals the presence of a mediastinal mass.
Based on the image shown, what is your diagnosis?

!["Patients [with cancer] and physicians would rather have a fixed-duration treatment, if possible," said Julie M. Vose, MD, MBA, at SOHO 2026.](https://cdn.sanity.io/images/0vv8moc6/cancernetwork/1cfb57db416943d8f8690afb0bc0d13aa3d90683-400x400.jpg?w=350&fit=crop&auto=format)



