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Opinion|Videos|September 15, 2023

Common Testing Strategies for Molecular Markers in mCRC

Author(s)Tanios S. Bekaii-Saab, MD, FACP, Daniel Ahn, DO, Christina Wu, MB, BCh, MD

Experts emphasize the importance of acquiring both tissue and circulating tumor DNA (ctDNA) for molecular testing in patients with metastatic colorectal cancer, address challenges such as lack of tissue and costs, and highlight the role of HER2 as a biomarker.

Episodes in this series

EP. 1 An Overview of Colorectal Cancer (CRC)

EP. 1 An Overview of Colorectal Cancer (CRC)

EP. 2 The Evolving Landscape of Biomarker Testing in Metastatic Colorectal Cancer (mCRC)

EP. 2 The Evolving Landscape of Biomarker Testing in Metastatic Colorectal Cancer (mCRC)

EP. 3 Common Testing Strategies for Molecular Markers in mCRC

EP. 3 Common Testing Strategies for Molecular Markers in mCRC

EP. 4 Patient Scenario: A 65-Year-Old Man with HER2+ mCRC

EP. 4 Patient Scenario: A 65-Year-Old Man with HER2+ mCRC

EP. 5 MOUNTAINEER-01 Trial: Tucatinib in Patients With mCRC

EP. 5 MOUNTAINEER-01 Trial: Tucatinib in Patients With mCRC

EP. 6 DESTINY-CRC02 Trial: Trastuzumab Deruxtecan for the Management of mCRC

EP. 6 DESTINY-CRC02 Trial: Trastuzumab Deruxtecan for the Management of mCRC

EP. 7 Approaches for Treatment Sequencing in Patients With HER2+ mCRC

EP. 7 Approaches for Treatment Sequencing in Patients With HER2+ mCRC

EP. 8 Patient Scenario: A 66-Year-Old Male With BRAF-Mutant mCRC

EP. 8 Patient Scenario: A 66-Year-Old Male With BRAF-Mutant mCRC

EP. 9 The Role of BRAF in mCRC

EP. 9 The Role of BRAF in mCRC

EP. 10 BEACON Study: Encorafenib, Binimetinib, and Cetuximab in BRAF-Mutant mCRC

EP. 10 BEACON Study: Encorafenib, Binimetinib, and Cetuximab in BRAF-Mutant mCRC

EP. 11 BREAKWATER Study: Encorafenib, Cetuximab, and Chemotherapy for BRAF-Mutant mCRC

EP. 11 BREAKWATER Study: Encorafenib, Cetuximab, and Chemotherapy for BRAF-Mutant mCRC

EP. 12 The Future of BRAF-Mutant mCRC Management

EP. 12 The Future of BRAF-Mutant mCRC Management

EP. 13 Future CRC Treatment to Focus on Mutation Status, Expert Says

EP. 13 Future CRC Treatment to Focus on Mutation Status, Expert Says

Personalized therapy tailored for mutation status is something to expect in the coming years for colorectal cancer treatment, notes Tanios S. Bekaii-Saab, MD.

EP. 14 Tanios S. Bekaii-Saab, MD, Speaks to Expanding Horizons in CRC Treatment

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21st Annual New York Lung Cancers Symposium®

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21st Annual New York Lung Cancers Symposium®

November 14, 2026

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