Database lists somatic EGFR mutations

GENEVA-A free online database brings together data on all of the known somatic mutations in EGFR, coupled with data on the response of NSCLCs treated with tyrosine kinase inhibitors, Samuel Murray, PhD, of Metropolitan Hospital, Athens, Greece, reported at the 1st European Lung Cancer Conference (abstract 750). A literature search identified 202 eligible peer-reviewed articles on somatic mutations in EGFR pertaining to NSCLC. Of 12,244 screened NSCLC patients, 3,381 had EGFR mutations, including 254 different mutations. The database, which is updated every 6 months, is available at www.EGFR-mutations.org.