Discussion Surrounding the Definition of Cure in Multiple Myeloma

The faculty consider how they would answer a patient who is 5 years out from a single infusion in sustained MRD-negative remission and asks whether they are cured. They refer to the provisional International Myeloma Society and International Myeloma Working Group definition of cure and describe how they use the words cure and long-term remission with patients. The panel also discusses the appeal of time off therapy, including quality of life, financial and time, and how the cost of CAR-T compares with continuous therapy.