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Opinion|Videos|November 24, 2023

Future Perspectives in the Treatment of Chronic Lymphocytic Leukemia

Author(s)Ricardo Parrondo, MD, Asher A. Chanan-Khan, MBBS, MD, Pooja Advani, MBBS, MD

Concluding their discussion, Drs Advani, Parrondo, and Chanan-Khan conclude that second-generation BTK inhibitors are the preferred first-line treatment in patients with chronic lymphocytic leukemia due to better efficacy and lower cardiovascular risk, with emerging therapies promising even better outcomes.

Episodes in this series

KOLs smiling at camera.

EP. 1 Clinical Case Scenario: A 55-Year-Old Patient With Chronic Lymphocytic Leukemia (CLL)

KOLs smiling at camera.

EP. 2 Currently Available Treatment Options for Patients With CLL

KOLs smiling at camera.

EP. 3 The Role of BTKi Monotherapy for CLL

KOLs smiling at camera.

EP. 4 Firstline BTKi Monotherapy in Patients With CLL: 4-Year Follow-Up Data from SEQUOIA

KOLs smiling at camera.

EP. 5 Firstline BTKi Monotherapy in Patients With CLL: 4-Year Follow-Up Data from ELEVATE-TN

KOLs smiling at camera.

EP. 6 Influence of BTKi-Related Adverse Event Patterns on Treatment Selection for Patients With CLLTN

EP. 7 The Role of Combination Venetoclax and BTKi Therapy for Firstline Treatment of CLL

EP. 7 The Role of Combination Venetoclax and BTKi Therapy for Firstline Treatment of CLL

EP. 8 Treatment Approaches in CLL After Disease Progression Following Combination Therapy With Venetoclax and BTKi

EP. 8 Treatment Approaches in CLL After Disease Progression Following Combination Therapy With Venetoclax and BTKi

EP. 9 Clinical Case Scenario: Managing a Diagnosis of Atrial Fibrillation

EP. 9 Clinical Case Scenario: Managing a Diagnosis of Atrial Fibrillation

$EP. 10 Goals of Treatment for Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia (R/R CLL)$

EP. 10 Goals of Treatment for Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia (R/R CLL)

EP. 11 Role of Second-Generation BTKis in R/R CLL: Key Efficacy and Safety Data

EP. 11 Role of Second-Generation BTKis in R/R CLL: Key Efficacy and Safety Data

EP. 12 Mechanisms of Resistance Observed With Covalent BTKis in CLL

EP. 12 Mechanisms of Resistance Observed With Covalent BTKis in CLL

EP. 13 Clinical Case Scenario: Management Strategies for BTKi Intolerance in Patients With CLL

EP. 13 Clinical Case Scenario: Management Strategies for BTKi Intolerance in Patients With CLL

EP. 14 Zanubrutinib in Patients with CLL and Intolerance to Prior BTKIs: Updated Phase 2 Study Data

EP. 14 Zanubrutinib in Patients with CLL and Intolerance to Prior BTKIs: Updated Phase 2 Study Data

EP. 15 BTK Inhibitor Treatment Strategies in Chronic Lymphocytic Leukemia

EP. 15 BTK Inhibitor Treatment Strategies in Chronic Lymphocytic Leukemia

EP. 16 Key Data on Hypertension and Atrial Fibrillation in Patients With CLL

EP. 16 Key Data on Hypertension and Atrial Fibrillation in Patients With CLL

EP. 17 Impact of Treatment Duration on Development of BTKi-Related Atrial Fibrillation in Patients With CLL

EP. 17 Impact of Treatment Duration on Development of BTKi-Related Atrial Fibrillation in Patients With CLL

EP. 18 Comparing Management of Hypertension versus Atrial Fibrillation in CLL

EP. 18 Comparing Management of Hypertension versus Atrial Fibrillation in CLL

EP. 19 Future Perspectives in the Treatment of Chronic Lymphocytic Leukemia

EP. 19 Future Perspectives in the Treatment of Chronic Lymphocytic Leukemia

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