|Articles|May 1, 2006

Oncology NEWS International

Oncology NEWS International Vol 15 No 5
Volume 15
Issue 5

Genentech Files sBLA for Avastin for First-Line NSCLC Treatment

SOUTH SAN FRANCISCOGenentech Inc. has submitted a supplemental Biologics License Application (sBLA) to FDA for bevacizumab (Avastin) in combination with platinum-based chemotherapy for first-line treatment of advanced, non-squamous, non-small-cell lung cancer (NSCLC). The company has requested priority review on the submission. In a phase III trial (E4599) in patients with locally advanced, metastatic, or recurrent NSCLC, Avastin plus paclitaxel and carboplatin improved overall survival by 25%, compared with chemotherapy alone.

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Genentech Files sBLA for Avastin for First-Line NSCLC Treatment

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