|Articles|May 1, 2006

Oncology NEWS International

  • Oncology NEWS International Vol 15 No 5
  • Volume 15
  • Issue 5

Genentech Files sBLA for Avastin for First-Line NSCLC Treatment

Genentech Files sBLA for Avastin for First-Line NSCLC Treatment

SOUTH SAN FRANCISCO—Genentech Inc. has submitted a supplemental Biologics License Application (sBLA) to FDA for bevacizumab (Avastin) in combination with platinum-based chemotherapy for first-line treatment of advanced, non-squamous, non-small-cell lung cancer (NSCLC). The company has requested priority review on the submission. In a phase III trial (E4599) in patients with locally advanced, metastatic, or recurrent NSCLC, Avastin plus paclitaxel and carboplatin improved overall survival by 25%, compared with chemotherapy alone.

Articles in this issue

about 20 years ago

NCCN Soft-Tissue Extremity Sarcoma Guidelines Clarify Follow-up Schedule

about 20 years ago

RFA Effective for Single, Small Hepatocellular Carcinoma

about 20 years ago

New Imaging, ChemoRT Recommendations From NCCN

about 20 years ago

Panitumumab Improves PFS in Advanced Colon Ca

about 20 years ago

Studies Question Watchful Waiting for Some Prostate Ca Pts

about 20 years ago

Growing Evidence Supports Stem Cell Hypothesis of Cancer

about 20 years ago

FDA Approves New Every-3-Week Dosing for Aranesp

about 20 years ago

Telephone Often Delivers News of Breast Cancer Diagnosis

about 20 years ago

IND Submitted for CYT-500

about 20 years ago

Lower-Dose Thalidomide Effective in Relapsed or Refractory Multiple Myeloma, With Less Toxicity

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