In this video, Dr. Sledge discusses what the negative results of the ALTTO trial mean for women with HER2-positive breast cancer.
George W. Sledge, Jr, MD, division of oncology at the Stanford University Medical Center, discusses the results of the ALTTO trial (Adjuvant Lapatinib and/or Trastuzumab Treatment Optimisation). Following surgery, the trial randomized patients with HER2-positive breast cancer into four treatment arms: trastuzumab alone, lapatinib alone, trastuzumab followed by lapatinib (sequential therapy), or the combination of the two drugs (concurrent therapy).
In this video, Dr. Sledge shares with our audience how despite the negative result, data from this trial may be used to inform other clinical trials, and discusses what other ongoing trials oncologists will be looking at to address questions about adjuvant therapy for women with HER2-positive breast cancer.
Frontline Chemo-Free Regimen Supported in HR+/HER2+ Breast Cancer Therapy
January 1st 2024Combining anastrozole with palbociclib, trastuzumab, and pertuzumab as a frontline therapy for hormone receptor–positive, HER2-positive breast cancer may avoid some of the toxicities associated with chemotherapy, says Amy Tiersten, MD.
Oncology On-The-Go Podcast: ASCO 2023 Recap
June 19th 2023Experts from University of California, Los Angeles Health and Mayo Clinic discuss key data presented at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting in the gynecologic and gastrointestinal cancer spaces and how they may impact patient care.