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Opinion|Videos|June 26, 2024

Monitoring Adverse Events Following CAR T-Cell Therapy

A panel of oncologists in academic and community settings discuss patient monitoring practices following CAR T-cell infusions, with a focus on neurotoxicities.

Episodes in this series

Video 1 - 4 KOLs are featured in "Identifying Potential Candidates for CAR T-Cell Therapy"

EP. 1 Identifying Potential Candidates for CAR T-Cell Therapy

Video 1 - 4 KOLs are featured in "Treating Patients Referred to Academic Centers for CAR T"

EP. 2 Treating Patients Referred to Academic Centers for CAR T

Video 1 - 4 KOLs are featured in "CAR T-Cell Therapy: Leukapheresis Practices"

EP. 3 CAR T-Cell Therapy: Leukapheresis Practices

Video 1 - 4 KOLs are featured in "Triaging and Prioritizing Patients with Multiple Myeloma"

EP. 4 Triaging and Prioritizing Patients with Multiple Myeloma

4 KOLs are featured in this program.

EP. 5 Transitioning Patients Back to Community Practices Following CAR T

4 KOLs are featured in this program.

EP. 6 Monitoring Adverse Events Following CAR T-Cell Therapy

4 KOLs are featured in this program.

EP. 7 Educating Patients on Complications Associated with CAR T-Cell Therapy

4 KOLs are featured in this program.

EP. 8 Improving Access for Patients Receiving CAR T-Cell Therapy

A panel of 4 experts on multiple myeloma

EP. 9 Collaborative Education for CAR T-Cell Therapy

EP. 10 Evaluating the Use of CAR T-Cell Therapy for Multiple Myeloma in Academic and Community Settings

EP. 10 Evaluating the Use of CAR T-Cell Therapy for Multiple Myeloma in Academic and Community Settings

Dr. Usmani: What is your protocol for monitoring and grading of neurotoxicity, cytokine release syndrome (CRS), and other acute toxicities immediately following CAR-T cell infusion?
1. Are there any subgroups of patients you have found to be at particularly high risk for delayed neurotoxicity requiring extended monitoring?
2. What are your institutional guidelines around administering steroids, anti-seizure medications, or other treatments for severe neurotoxicity?

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