Identifying Potential Candidates for CAR T-Cell Therapy
A panel of experts on multiple myeloma introduce themselves and discuss the initial process of identifying patients who are potential candidates for CAR T-cell therapy.
Could you describe the initial process of identifying and referring potential candidates for CAR T-cell therapy from the community setting to an academic center?
What patient specific factors might you consider?
Are there any criteria that patients need to meet in order to be ready to move to a community setting?Does this vary between community settings?
What are some challenges you are seeing when transitioning from community to academic settings?
Saad Z. Usmani, MD, MBA, FACP, FASCO, discussed quadruplet induction, extended maintenance, and when a community clinician should call a myeloma center.
Saad Z. Usmani, MD, MBA, FACP, FASCO, discussed the threshold he will act on in standard-risk disease, and the trial that would make the decision firmer.
In a phase 2 trial, CD38-targeted immune-PET detected active multiple myeloma in some patients with no signs of disease on standard fluorodeoxyglucose PET/CT.