Opinion|Videos|June 26, 2024
Transitioning Patients Back to Community Practices Following CAR T
Members of the panel discuss their criteria for determining when a patient is ready to transition back to community oncologists after they receive CAR T-cell therapy.
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Episodes in this series
- Dr. Krishnan: What criteria or thresholds do you use to determine when a patient is ready for transition back to the community oncologist after CAR-T therapy? (e.g. time since infusion, resolution of toxicities, evidence of response)
- Dr. Park: At what point in the patient's recovery course after CAR-T do you think it is ideal for their care to transition back to the community oncologist? What factors influence this timing?
- How much clinical/treatment detail from the CAR-T process at the academic center is typically provided or needed by community providers for optimal long-term monitoring and follow-up of the patient?
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Hans C. Lee, MD, discussed how community oncologists with limited access to MRD testing can think about the new IMS/IMWG definition of cure in myeloma.
Hans C. Lee, MD, discussed how he monitors patients with multiple myeloma who achieve deep, sustained MRD negativity after coming off therapy.
![“[W]e should strive to increase the [number] of patients…who enjoy long-term disease-free survival and possibly cure,” said Meletios Dimopoulos, MD.](https://cdn.sanity.io/images/0vv8moc6/cancernetwork/c7abebf9344f9b1be9aee80d9879d139c1655bcc-1200x1197.jpg?w=350&fit=crop&auto=format)
“[W]e should strive to increase the [number] of patients…who enjoy long-term disease-free survival and possibly cure,” said Meletios Dimopoulos, MD.
Pieter Sonneveld, MD, PhD, explained how sustained MRD negativity with DVRd in the PERSEUS trial may guide long-term outcome counseling in multiple myeloma.
Hematologic specialists discussed where ciltacabtagene autoleucel fits in the treatment paradigm at first relapse and beyond in multiple myeloma.
Updated NCCN Guidelines for multiple myeloma add a dedicated MRD testing framework and expand recommended MRD assessment timepoints.
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