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|Articles|December 1, 1997

Oncology NEWS International

  • Oncology NEWS International Vol 6 No 12
  • Volume 6
  • Issue 12

Patients Sought for New Trial of Adoptive Immunotherapy

CHICAGO-Researchers from three midwestern centers are seeking patients with leukemia, lymphoma, or multiple myeloma who have relapsed after an allogeneic stem cell transplant for a new trial of adoptive immunotherapy.

CHICAGO—Researchers from three midwestern centers are seeking patients with leukemia, lymphoma, or multiple myeloma who have relapsed after an allogeneic stem cell transplant for a new trial of adoptive immunotherapy.

The concept of the study is that lymphocyte infusions from the original donor may induce remission. However, this approach may also be complicated by graft-versus-host disease (GVHD).

The researchers will attempt remission induction by infusion of IL-2-activated lymphocytes transduced with the herpes simplex thymidine kinase (HSTK) gene. If severe GVHD occurs, the infused lymphocytes will be killed by adminis-tration of the prodrug ganciclovir (Cytovene).

For referrals, contact Dr. Richard Burt at Northwestern University (312-908-5400), Dr. William Drobyski or Dr. William Burns at the Medical College of Wisconsin, Milwaukee (414-257-5452), or Dr. Charles Link at the Human Gene Therapy Research Institute, Des Moines, Iowa (515-241-8790).

Articles in this issue

over 28 years ago

Team-Based Approach to Managed Specialty Care

over 28 years ago

Children’s Art Project at M.D. Anderson

over 28 years ago

Office of Cancer Survivorship Grants Awards for First 20 Studies

over 28 years ago

Laparoscopic Colectomy May Prove Equivalent to Open Surgery

over 28 years ago

Advice on Negotiating BMT Service Contracts

over 28 years ago

Komen Debuts New Websites on Breast Cancer

over 28 years ago

‘MDs Too Often Fail to Give Adequate Analgesic Doses’

over 28 years ago

Breach of Fiduciary Duty-How to Defend Against It

over 28 years ago

Survivors Help Women Deal With Breast Cancer Diagnosis

over 28 years ago

University of Utah’s Huntsman Cancer Institute Joins NCCN

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