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Opinion|Videos|September 20, 2024

Role of Histology and Data in Selecting Optimal Therapy in nccRCC

Author(s)Moshe Ornstein, MD, MA, Karine Tawagi, MD, Hans Hammers, MD

Medical experts explore how non–clear cell RCC histology impacts treatment selection, addressing challenges with less common subtypes vs more frequent ones, and discuss how clinical data and experience inform treatment sequencing and shared decision-making.

Episodes in this series

EP. 1 Overview of RCC: Clear-Cell and Non–clear Cell

EP. 1 Overview of RCC: Clear-Cell and Non–clear Cell

EP. 2 Challenges in Treating RCC From Community and Academic Settings

EP. 2 Challenges in Treating RCC From Community and Academic Settings

EP. 3 Non–clear Cell RCC: First-Line Treatment Options and Guideline Updates

EP. 3 Non–clear Cell RCC: First-Line Treatment Options and Guideline Updates

EP. 4 KEYNOTE-B61: Clinical Implications of Efficacy and Safety Data in Practice

EP. 4 KEYNOTE-B61: Clinical Implications of Efficacy and Safety Data in Practice

EP. 5 nccRCC: Alternative Therapies

EP. 5 nccRCC: Alternative Therapies

EP. 6 Role of Histology and Data in Selecting Optimal Therapy in nccRCC

EP. 6 Role of Histology and Data in Selecting Optimal Therapy in nccRCC

EP. 7 AE Management of IO/TKI and Future of nccRCC

EP. 7 AE Management of IO/TKI and Future of nccRCC

EP. 8 KEYNOTE-564: Pembrolizumab as Adjuvant Therapy

EP. 8 KEYNOTE-564: Pembrolizumab as Adjuvant Therapy

EP. 9 NCCN Guideline Updates in Clear-Cell RCC

EP. 9 NCCN Guideline Updates in Clear-Cell RCC

EP. 10 Best Treatment Selection in Clear-Cell RCC

EP. 10 Best Treatment Selection in Clear-Cell RCC

Video content above is prompted by the following:

How does the histology of nccRCC affect treatment selection?

What challenges are often faced when treating a patient with a less frequent subtype (collecting duct, renal medullary) vs.vs a more frequent subtype (papillary, chromophobe)?

How do you utilize both clinical data and experience in your approach to treatment sequencing?

How do you facilitate shared discussion decision-making in treatment selection?

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