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|Articles|August 1, 2006

Oncology NEWS International

  • Oncology NEWS International Vol 15 No 8
  • Volume 15
  • Issue 8

Takeda Signs Agreement With Galaxy Biotech for HuL2G7

Takeda Pharmaceutical has signed an exclusive licensing agreement with Galaxy Biotech (Mountain View, California) to develop, manufacture, and market HuL2G7, a recombinant humanized anti-hepatocyte growth factor (anti-HGF) monoclonal antibody developed by Galaxy Biotech. HGF is believed to mediate proliferation, metastasis, antiapoptosis, and neoangiogenesis of many types of tumors. In animal models, treatment of intracranial glioma xenografts with HuL2G7 induced substantial tumor regression and prolonged survival (Clin Cancer Res 12:1292-1298, 2006).

TOKYO, Japan—Takeda Pharmaceutical has signed an exclusive licensing agreement with Galaxy Biotech (Mountain View, California) to develop, manufacture, and market HuL2G7, a recombinant humanized anti-hepatocyte growth factor (anti-HGF) monoclonal antibody developed by Galaxy Biotech. HGF is believed to mediate proliferation, metastasis, antiapoptosis, and neoangiogenesis of many types of tumors. In animal models, treatment of intracranial glioma xenografts with HuL2G7 induced substantial tumor regression and prolonged survival (Clin Cancer Res 12:1292-1298, 2006).

Articles in this issue

about 19 years ago

Younger Age at Brain Tumor Diagnosis Portends Poor Emotional Outcome

about 19 years ago

Higher Responses in Metastatic Colon Ca When Cetuximab Added to Chemo

about 19 years ago

Triple Targeted Therapy Is Tested in Pts With Solid Tumors

about 19 years ago

FDA Approves Three-Drug Combination Tablet for HIV-1

about 19 years ago

Side Effects Persist 16 Years After Prostate Ca Brachytherapy

about 19 years ago

No Significant QOL Differences for Raloxifene and Tamoxifen

about 19 years ago

Amrubicin Appears Promising in Small-Cell Lung Cancer

about 19 years ago

R-MP Active in Older Pts With Newly Diagnosed Myeloma

about 19 years ago

Sunitinib and Sorafenib Active in Phase II Advanced NSCLC Trials

about 19 years ago

Experimental Regimens Fail to Boost Pancreatic Survival

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