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Opinion|Videos|March 21, 2025

TRANSFORM Safety Summary

Author(s)Mazyar Shadman, MD, MPH, Melody Smith, MD, MS

Experts provide a safety summary of the phase 3 TRANSFORM study, highlighting key safety findings for liso-cel in relapsed/refractory large B-cell lymphoma.

Episodes in this series

EP. 1 Brief Overview of Current Treatment Landscape and Unmet Needs in R/R Large B-Cell Lymphoma

EP. 1 Brief Overview of Current Treatment Landscape and Unmet Needs in R/R Large B-Cell Lymphoma

EP. 2 Three-Year Follow-Up From Phase 3 TRANSFORM: Study Overview and Key Efficacy Data

EP. 2 Three-Year Follow-Up From Phase 3 TRANSFORM: Study Overview and Key Efficacy Data

EP. 3 Long-Term Efficacy and Real-World Outcomes With Liso-cel

EP. 3 Long-Term Efficacy and Real-World Outcomes With Liso-cel

EP. 4 Patient Selection and Timing Considerations for CAR T Therapy

EP. 4 Patient Selection and Timing Considerations for CAR T Therapy

EP. 5 Impact of Manufacturing and Treatment Timing on Patient Outcomes for CAR T in R/R LBCL

EP. 5 Impact of Manufacturing and Treatment Timing on Patient Outcomes for CAR T in R/R LBCL

EP. 6 Clinical Features and Risk Factors: Navigating ASCT vs CAR T Therapy Decisions in R/R LBCL

EP. 6 Clinical Features and Risk Factors: Navigating ASCT vs CAR T Therapy Decisions in R/R LBCL

EP. 7 TRANSFORM Safety Summary

EP. 7 TRANSFORM Safety Summary

EP. 8 Safety Management and Monitoring Protocols for Liso-cel

EP. 8 Safety Management and Monitoring Protocols for Liso-cel

EP. 9 Future Directions and Key Insights in LBCL Treatment

EP. 9 Future Directions and Key Insights in LBCL Treatment

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