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|Articles|January 1, 1996

Oncology NEWS International

  • Oncology NEWS International Vol 5 No 1
  • Volume 5
  • Issue 1

Zoladex Gets Indication for Advanced Breast Ca

WILMINGTON, Del--Zoladex (goserelin acetate implant), Zeneca Pharmaceuticals' gonadotropin-releasing-hormone (GnRH) agonist, has received approval for use in the treatment of advanced breast cancer in premenopausal and perimenopausal women.

WILMINGTON, Del--Zoladex (goserelin acetate implant), Zeneca Pharmaceuticals'gonadotropin-releasing-hormone (GnRH) agonist, has received approvalfor use in the treatment of advanced breast cancer in premenopausaland perimenopausal women.

The agent was introduced in the United States for the treatmentof advanced prostate cancer in 1989 and for the treatment of endometriosisin 1993.

Zoladex, given by injection once a month, acts on the pituitarygland to cause decreased production of estrogen by the ovaries.This lowers serum estrogen levels to concentrations typical ofpostmenopausal women, reducing estrogen stimulation of breasttumor growth.

The new indication is based on results of clinical trials involvingmore than 800 women in North America and Europe, showing responserates and survival benefits comparable to those achieved by oophorectomy,the company said.

Articles in this issue

about 30 years ago

HCFA Reevaluations May Affect Chemo Administration Cost Codes

about 30 years ago

Breast Cancer Info Now on Internet

about 30 years ago

HDC/ABMT Has Benefits in Multiple Myeloma

about 30 years ago

Clinical Trial to Study MoAb 17-1A as An Adjuvant to Colon Cancer Therapy

about 30 years ago

Reporting of Study Comparing Casodex, Eulexin Is Questioned

about 30 years ago

Limits on Tamoxifen Duration Questioned

about 30 years ago

ACRO Forecasts Radiologist Surplus

about 30 years ago

Potency Status Before RT, Not Dose, Determines Post-RT Function

about 30 years ago

Dr. Klausner Outlines Goals for NCI

about 30 years ago

Difficulties in Translating Relative Risks Into Absolute Risk

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