Leah Lawrence

Single-agent blinatumomab demonstrated antileukemia activity in pediatric patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (BCP-ALL) in a recently published phase I/II study.

Serum levels of a vitamin D biomarker measured at the time of breast cancer diagnosis were independently associated with breast cancer prognosis, especially among premenopausal women.

The combination of ATRA and arsenic trioxide for the treatment of low- or intermediate-risk acute promyelocytic leukemia had advantages compared with ATRA plus chemotherapy.

Myocarditis is a rare and sometimes lethal complication of combination immune checkpoint blockade for metastatic melanoma.

Patient age was found to be significantly associated with mortality from papillary thyroid cancer in a linear fashion with no apparent age cut point.

A new paper highlights the global inequities in access to prevention, early detection and treatment for breast cancer and cervical cancer.

Results of a meta-analysis revealed that BRAF/MEK and PD-1 inhibition significantly improved survival in BRAF-mutated melanoma compared with other treatments.

Treatment at a facility with a higher patient volume was associated with a lower risk of mortality for patients with multiple myeloma, even after adjustment for sociodemographic and geographic factors and comorbidities.

Cancer survivors in the United States were taking medications to treat depression and anxiety at almost twice the rate of the general population between 2010 and 2013.

A phase II study of sonepcizumab has failed to meet its primary progression-free survival endpoint in patients with metastatic renal cell carcinoma.

Undergoing a lobectomy for thyroid nodules suspicious for papillary thyroid cancer on fine-needle aspiration was more cost effective and was associated with greater effectiveness compared with total thyroidectomy.

Chronic infection with hepatitis B or C virus was associated with an increased risk for non-Hodgkin lymphoma among patients with HIV who are on antiretroviral therapy.

A new study from the ACS indicates that the proportion of cancer deaths from cigarette smoking varies substantially by state, but is highest in the South where as many as 40% of cancer deaths in men are smoking-related.

Maintenance therapy with norethandrolone significantly improved survival in elderly patients with acute myeloid leukemia without increasing toxicity.

Patients with peritoneal metastatic colorectal cancer had significantly shorter overall survival compared with patients with other isolated sites of metastases.

The addition of the IMA901 vaccine to sunitinib for the first-line treatment of metastatic renal cell carcinoma did not improve overall survival.

Waiting as long as 3 months from a melanoma diagnosis to sentinel lymph node biopsy had no effect on 5-year survival or sentinel node positivity rate, according to the results of a study.

Frontline intensive therapy with rituximab plus high-dose sequential chemotherapy did not improve outcomes for high-risk patients with DLBCL compared with treatment with R-CHOP-14.

Longer durations of maintenance therapy with lenalidomide were associated with longer survival among patients who underwent autologous hematopoietic stem cell transplant for multiple myeloma.

Patients with myeloproliferative neoplasms revealed discrepancies between patient and physician recollection of management and communication in a research survey.

Former chairs of the USPSTF are questioning whether it may be time to alter the relationship between the USPSTF and determinations of preventive services coverage under the Patient Protection and Affordable Care Act.

A new study has found that the price of older drugs increased more between 2010 and 2015 than that of newer drugs, with some having undergone dramatic price increases.

Treatment with cabozantinib resulted in significantly improved PFS and overall response vs sunitinib for patients with metastatic renal cell carcinoma.

Use of the targeted therapy dabrafenib resulted in a high overall response rate and was well tolerated in a small phase I/II study of pediatric BRAF V600-mutant low-grade glioma.

Prediagnosis obesity as measured by body mass index was a risk factor for overall and individual secondary primary cancers in a study of male cancer survivors.

Patients with renal cell carcinoma at high risk for recurrence had prolonged disease-free survival when treated with sunitinib compared with placebo.

A large percentage of patients with metastatic melanoma in Europe may not have access to innovative medicines used to treat the disease, according to the results of a survey.

The use of the PD1 inhibitor nivolumab appeared to be feasible and safe in a small study of patients with untreated, stage I–IIIa non–small-cell lung cancer.

Melanoma patients diagnosed prior to age 18 had a higher survival vs adult patients, despite having similar tumor depth and more frequent nodal metastases.

Identifying certain characteristics of BRAF-positive and RAS-positive thyroid cancers may help define a molecular profile for the disease.