P. K. Morrow, MD | Authors

MERCY PRIMARY CARE

SUITE100 BUILDING 1

275 CURRY HOLLOW RD

Articles

Bone Biology and the Role of the RANK Ligand Pathway

December 30, 2009

Bone renewal is essential for bone strength. During childhood and early adulthood, bone formation prevails over bone resorption, as bones increase in size and strength. Peak bone mass is achieved during the third decade in life, with a higher peak bone mass being protective against osteoporosis later in life.[1] Bone loss is most prominent in women at menopause due to the effects of a natural decline in estrogen levels. However, bone mass begins to decrease with age, and bone loss is most prominent in women at menopause due to the effects of a natural decline in estrogen levels.[2]