Articles by Roy E. Smith, MD

UFT/Leucovorin vs 5-FU/Leucovorin in Colon Cancer
ByRoy E. Smith, MD,Barry C. Lembersky, MD,H. Samuel Wieand, PhD,Linda Colangelo, MS,Eleftherios P. Mamounas, MD, MPH Adjuvant chemotherapy has been shown to alter the natural history of resected colon cancer. Two regimens (fluorouracil [5-FU] plus leucovorin and 5-FU plus levamisole) have been found to prolong disease-free survival and overall survival in affected patients.

UFT Plus Calcium Folinate vs 5-FU Plus Calcium Folinate in Colon Cancer
ByRoy E. Smith, MD,D. Lawrence Wickerham, MD,H. Samuel Wieand, PhD,Linda Colangelo, MS,Eleftherios P. Mamounas, MD, MPH Adjuvant chemotherapy has been shown to alter the natural history of resected colon cancer. Two regimens (5-fluorouracil [5-FU] plus calcium folinate and 5-FU plus levamisole [Ergamisol]) have been found to prolong

Drs. Peeters and Haller provide a thorough review of the recent historical development, current state of knowledge, and future of adjuvant therapy for early-stage colon and rectal cancers. They provide reasonable recommendations for the