Acute Lymphoblastic Leukemia | Topics

KTE-X19 Safe, Efficacious as Therapy for Pediatric B-Cell ALL in ZUMA-4
June 18, 2021

Results of the phase 1 portion of ZUMA-4 support continued investigation into the efficacy of KTE-X19 in pediatric patients with B-cell acute lymphoblastic leukemia.

Allogeneic CAR T-Cell Therapy in R/R Large B-Cell Lymphoma Demonstrates Efficacy Signals
June 14, 2021

Data presented at 2021 ASCO indicated that chimeric antigen receptor therapy with ALLO-501A plus ALLO-647 lymphodepletion showed promise in patients with relapsed/refractory large B-cell lymphoma.

HSCT-Sparing, Chemotherapy-Free Treatment of Ph+ ALL With Ponatinib/Blinatumomab Leads to 100% CR Rate
June 05, 2021

Successful treatment of patients with Philadelphia chromosome–positive acute lymphocytic leukemia was noted with ponatinib plus blinatumomab, denoted by complete and major molecular responses.