BETA
Your AI-Trained Oncology Knowledge Connection!
CHARTA Shows Survival Benefit of Four-Drug Regimen for Advanced CRC
This video examines results of the CHARTA trial, which tested first-line FOLFOX plus bevacizumab with or without irinotecan in patients with advanced colorectal cancer.
Second-Line Regorafenib Extends Survival in Sorafenib-Tolerant HCC Patients
This video examines an exploratory analysis of the RESORCE trial, which tested regorafenib vs placebo in hepatocellular carcinoma patients following radiographic progression on sorafenib.
Reducing Treatment Doses in Head and Neck Cancer to Improve QOL
In this video we discuss efforts to reduce treatment doses in order to lessen long-term side effects and improve quality of life among patients with head and neck cancers.
Menopause Symptoms Can Predict Tamoxifen Adherence for Breast Cancer Prevention
This video examines findings from the International Breast Cancer Intervention Study (IBIS-1), which found that patients with menopause symptoms were less likely to continue long-term tamoxifen therapy.
Study Finds ESR1 Mutations Drive Metastasis in ER-Positive Breast Cancer
This video looks at a new study that found that in addition to conferring resistance to hormone therapies, estrogen receptor mutations can cause breast cancer cells to metastasize.
Using KIR Genotyping to Improve Transplant Success
This interview examines the use of KIR genotyping during donor selection and its association with improved outcomes in patients undergoing allogeneic hematopoietic stem cell transplantation.
The Microbiome and Outcomes After Allogeneic Transplant
In this interview we discuss advances in the relationship between the microbiome and outcomes after allogeneic transplant, including graft-vs-host disease and relapse.
Treatment Approaches for Therapy-Related AML, MDS Based on Mutation Profiles
This video examines different mutational profiles of therapy-related myeloid neoplasms and how they can affect approaches to treatment.
Late Toxicity of Radiotherapy and Chemotherapy in Hodgkin Lymphoma
This interview examines treatment-related cardiotoxicity and the risk of second malignancy in patients with Hodgkin lymphoma.
QOL of Multiple Myeloma Patients Receiving Maintenance Therapy
This interview examines a study that looked at the health-related quality of life of multiple myeloma patients in a real-world setting who underwent maintenance therapy after autologous stem cell transplant.
Using FDG-PET to Guide Hodgkin Lymphoma Treatment
This interview examines the role of functional imaging to direct therapy (escalation or de-escalation) for early and advanced Hodgkin lymphoma.
Longer Term Data Confirm Subcutaneous Rituximab Efficacy in Follicular Lymphoma
In this video we discuss longer term results of the phase III SABRINA study, which tested the safety and efficacy of subcutaneous rituximab in patients with follicular lymphoma.
Adding Chemotherapy in Medulloblastoma Linked With Improved Survival
A recent retrospective study found that adding chemotherapy to postoperative treatment of craniospinal radiation for adults with medulloblastoma improves survival.
Study Identifies Effective PD-L1 Tests for Lung Cancer
A new study looking at PD-L1 expression lung cancer tissue has found that the SP142 assay shows significantly lower levels of PD-L1 expression compared with other available tests.
Radiation Boost Reduces Local Recurrence in DCIS Patients
A study presented last month at ASTRO found that a boost of radiation therapy following lumpectomy in DCIS patients resulted in reduced rates of local recurrence.
Higher Facility Volume Linked With Better Radiation Outcomes for Head and Neck Cancers
A study presented last month at ASTRO found that better radiation outcomes for head and neck cancer were associated with higher facility volume.
Role of Cyclic AMP in Leukemias
In leukemias, cyclic adenosine monophosphate (cAMP) can play a role in cancer cell maturation and can be both pro- and antiapoptotic.
Anti-Malarial, Anti-Fungal Drugs Show Promise in AML
Several anti-malarial and anti-fungal drugs might be able to overcome a previously unexploited mechanism that allows some leukemia cells to escape programmed cell death.
Upfront Management of Patients With Multiple Myeloma
In this video we discuss the initial symptoms and diagnosis of multiple myeloma as well as upfront treatment with autologous stem cell transplantation and newer agents.
Shared Decision-Making in Hematologic Malignancies
In this video we discuss the goals of shared-decision making in hematologic malignancies and touch upon different scenarios where its use may be appropriate.
