Oncology Vol 28 No 1S

Of the patients who were eligible for breast conservation therapy (BCT), younger age and being married were associated with choosing mastectomy.

Preoperative and postoperative patient and tumor characteristics for breast cancer patients treated at New York Presbyterian Hospital, Weill Cornell Medical College with Intrabeam intraoperative radiation therapy (IORT) are reported.

Although uncommon in women less than 40 years old, breast cancer in younger women may have unique biologic and treatment implications. The purpose of this study was to evaluate treatment of breast cancer in young women with respect to previously established clinical predictors of local therapy choice.

Results and outcomes of use of multicatheter interstitial high-dose-rate (HDR) brachytherapy (BT) to deliver accelerated partial-breast irradiation (APBI) in a large cohort of women treated in a three-physician private practice setting over 10 years and 9 months are reported.

Radiotherapy for left-sided breast cancer has historically been associated with an elevated risk of cardiac mortality, based upon studies in the era predating computed tomography (CT)-based treatment planning. This study assessed the impact of tumor laterality on overall survival (OS) in a large cohort treated with modern techniques to determine if left-sided treatment is still associated with a heightened risk of cardiac mortality.

Conventional radiotherapy (RT) with proton-based RT in a series of patients with right- or left-sided breast cancer and anatomical variations resulting in technically challenging radiation plans are compared.

Although autologous and immediate reconstruction has potential advantages when compared with delayed and implant-based reconstruction for patients with breast cancer (BCA), concerns exist for potential increased complications and technical difficulty in the delivery of postmastectomy radiotherapy (PMRT).

Breast cancer patients who develop a recurrence in the chest wall after mastectomy represent a high-risk subgroup that may benefit from early identification and more aggressive treatment. Traditional clinicopathologic factors have been proven useful for prognosis, but there remains a need to identify molecular markers with prognostic significance.

An investigation of the association between deteriorating economic environment and utilization of postlumpectomy radiation therapy (PLRT) using a difference-in-differences (DID) model.

Although recent data have been published regarding trends surrounding mastectomy with reconstruction for breast cancer, little data exist about predictors of immediate vs delayed reconstruction and the prevalence of reconstruction where it is traditionally contraindicated, such as inflammatory breast cancer and stage IV disease.

Significant effort has been expended over the past decade to reduce racial disparities in breast cancer care. Whether disparities in receipt of appropriate radiotherapy care for breast cancer persisted despite these efforts is unknown, as is the impact of being eligible for Medicare.

Patients with abnormal screening mammogram (abSM) often experience prolonged wait times for additional testing to resolve the cause of the abnormality. The purpose of this study was to initiate an intervention, termed ‘reflex testing’ (RefT), and analyze pre- and post-RefT timelines to determine if, where, and in whom RefT resulted in significant decreases in timelines for resolution of abSM of patients undergoing routine screening in an accredited community hospital-based breast center.

Due to the rarity of Paget disease (PD), the role of breast conserving surgery (BCS) and radiation therapy (RT) is not fully defined. The specific aims of this analysis are to study national patterns of care in the local management of PD and to determine breast cancer–specific survival (BCSS) by type of treatment in a large population-based cohort.

Recent expert consensus statements have endorsed use of accelerated partial-breast irradiation (APBI) in select groups of low-risk women with early-stage breast cancer. APBI in the form of balloon brachytherapy is increasingly selected as a method of radiation treatment (RT).

In breast cancer, the primary site residual burden of disease (PRBD) after neoadjuvant chemotherapy has been shown to correlate with poor prognostic outcomes. Currently, there is no established standard of care to offer patients with residual disease, in terms of adjuvant systemic treatment after full-dose neoadjuvant chemotherapy.

The World Health Organization predicts that 26.4 million new cancer cases will be reported in 2030 alone. It is necessary to establish an effective mentoring paradigm in radiological science, not just for medical students (MS) but also for high school (HS) and college undergraduate (UG) students, to promote a greater general awareness of the study of oncology as well as its therapeutic implementation.

There are over 3.0 million cases of nonmelanoma skin cancer (NMSC) diagnosed each year in the United States. Multiple treatment options exist for the treatment of these patients. We describe the outcomes of patients treated at a large private dermatology practice with electronic brachytherapy (eBx) who had a minimum follow-up duration of 1 year.

The long-term outcomes of radiation therapy (RT) in patients infected with human immunodeficiency virus (HIV) who have benign lymphoepithelial cysts (BLECs) of the parotid glands are reported.

Electronic brachytherapy for skin cancer is now available without the need for room shielding. Advances in radiobiology and radiotechnology permit the treatment course to be given in eight fractions over 4 weeks. This report describes the experience with our first 565 treated lesions.

Thymic tumors are a rare disease and have been treated in a similar manner without convincing data. We present our institutional results of outcomes between invasive thymoma and thymic carcinoma.

Patients who sustain brain and spinal cord injuries are at risk for developing neurogenic heterotopic ossification (NHO), the formation of bone in extraskeletal soft tissue. The purpose of this study was to review the experience and to report the outcome of eight consecutively irradiated joints in four patients with NHO.

Linear accelerator–based stereotactic radiosurgery (SRS) is a treatment option for melanoma patients who have developed brain metastases. Few data are available on treatment of patients with ≥ 5 lesions. We sought to determine the effectiveness of SRS in patients with ≥ 5 melanoma brain metastases.

In the United States, an estimated 48 million individuals live without health insurance. The purpose of this study is to explore differences in key factors associated with insurance status among non-Medicare-aged adults diagnosed with the top 25 incident cancers using the Surveillance, Epidemiology, and End Results (SEER) public-use database.

As the volume of radiation oncology information increases, the ability to gather and critically appraise high-quality information in order to answer clinical questions becomes increasingly challenging for radiation oncologists. Sharing knowledge about new information and practice variations is instrumental to high-quality radiation oncology practices.

The standard approach for palliation of bone metastasis (BM) is conventionally planned radiation (CRT). Randomized studies have shown the equivalence of hypofractionated vs conventionally fractionated regimens; yet, reported pain control is poor with either approach, resulting in some degree of pain relief in only 50% to 80% of cases and complete response in 15% to 60% of cases.

NRG Oncology is a member of the National Cancer Institute (NCI) National Clinical Trials Network program and was created by the integration of three adult cooperative groups: the National Surgical Adjuvant Breast and Bowel Project (NSABP), the Radiation Therapy Oncology Group (RTOG), and the Gynecologic Oncology Group (GOG). The Publications Working Group, has begun the amalgamation of three publications databases into one to track progress in manuscript development and to provide access to a comprehensive bibliography that incorporates the past/current research of all three legacy groups.

With the increasing patient population in the oncology world and advancing technologies in radiation oncology in particular, there is an increasing need for assistance in providing high-quality care.

This retrospective analysis concentrates on our institutional experience with transarterial radioembolization (TARE) for the treatment of liver metastasis from neuroendocrine cancer.

Advances in intensity-modulated radiation therapy (IMRT) head and neck target delineation and treatment planning have led to improved sparing of organs at risk (OARs). In this study, we compare three IMRT techniques for the treatment of common cases of oropharyngeal squamous cell carcinoma.

Step-and-shoot intensity-modulated radiation therapy (IMRT) and variable-dose-rate volumetric modulated arc therapy (VMAT) are two common treatment techniques for the definitive treatment of prostate cancer. In order to compare these two techniques in modern practice, we analyzed two cohorts of patients treated at our institution who were matched for PTV, prescribed dose, and patient characteristics.