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Your AI-Trained Oncology Knowledge Connection!
How Can We Improve Stress Levels in Cancer Patients?
Dianne Shumay, PhD, director of psycho-oncology at UCSF, weighs in on how we can use psychological interventions to improve stress levels in cancer patients.
Why Cancer Gene Variants are Frequently Reclassified
A study shows gene variants of uncertain significance are frequently reclassified, necessitating amended test result reports.
FDA Approves Next-Generation Sequencing Test For MRD Detection
The FDA authorized the first next-generation sequencing test to detect minimal residual disease in blood cancers.
Pazopanib Active in von Hippel-Lindau Disease
Patients with von Hippel-Lindau disease may have a new treatment option in the antiangiogenic therapy pazopanib.
Applying Nanotechnologies for Immunotherapy
Nanotechnological strategies are making preclinical strides toward more effective, less toxic, immunotherapies.
TRK Fusions Identified in Hematologic Cancers
A study shows TRK gene fusions in hematologic cancers may respond to larotrectinib.
Eighth Edition of AJCC/TNM Staging System Best at Detecting Survival in Thyroid Cancer
The eighth edition outperforms the seventh edition in predicting survival differences in patients with papillary thyroid cancer and follicular thyroid cancer.
Male Sex Ups Mortality Risk in BRAF V600E Papillary Thyroid Cancer
The study confirmed a significant effect of male sex on PTC-specific patient survival in individuals with the most frequent oncogenic mutation.
Holistic Cancer Therapy and Symptom Management
Professor Judi Fouladbakhsh speaks with Cancer Network about evidence-based holistic approaches to cancer care.
Targeting the Tumor Microenvironment May Aid in Treatment of Ovarian Cancer
Certain malignancies may possess a common and targetable matrix response, which affects disease pathogeneis, according to a study in Cancer Discovery.
Target Folate Receptor Alpha in Ovarian Cancer?
Dr. Dmitriy Zamarin speaks with Cancer Network about the findings of a phase II trial in platinum-resistant ovarian cancer patients.
Basal Cell Carcinomas a Clinical Marker for Malignancy Risk?
Individuals who develop frequent basal cell carcinomas may have an increased prevalence of germline mutations in DNA repair genes and an increased malignancy risk.
What Underlies PARP Inhibitor Resistance in Ovarian Cancer?
New research examines the mechanisms underlying why most patients with high-grade serous ovarian cancer develop resistance to PARP inhibitors.
Rates of Erectile Dysfunction Higher in Childhood Cancer Survivors
Linda Jacobs, PhD, CRNP, director of the Cancer Survivorship Center, comments on the incidence of erectile dysfunction in childhood cancer survivors.
Building a Better Mouse Model for High-Grade Serous Carcinoma
Researchers have developed a mouse model of high-grade serous carcinoma that could prove useful in the preclinical testing of prevention strategies for ovarian cancer.
Novel Early Screening Tool for Ovarian Cancer
Optical coherence tomography and multispectral fluorescence imaging have demonstrated promising results in the early detection of ovarian cancer.
Using Integrative Medicine Approaches for Cancer-Related Fatigue
Breast and gynecologic cancer patients undergoing chemotherapy may experience improvement in cancer-related fatigue with integrative medicine approaches.
Population Testing to Prevent Gynecologic Cancers
Dr. Ranjit Manchanda speaks with Cancer Network about using population testing to predict and prevent gynecologic cancers.
Nuclear Pore Proteins May Be Effective Anti-Cancer Targets for Prostate Cancer
A particular gatekeeper-the nuclear pore protein called POM121-traffics molecules that increase tumor aggressiveness in prostate cancer.
Sarcoma-Associated Gene Fusions a Result of ‘Genome Chaos’
A study finds EWSR1-ETS in 42% of cases via complex, loop-like rearrangements, rather than by simple reciprocal translocations.
Mogamulizumab Approved for Two Rare Types of Cutaneous T-cell Lymphoma
Mogamulizumab (Poteligeo) is indicated for relapsed or refractory mycosis fungoides or Sézary syndrome following at least one prior systemic therapy.
Gene Variant Linked to Risk of Oral Squamous Cell Carcinoma
A study shows significant association between MTHFR C677T polymorphisms and risk of oral squamous cell carcinoma.
Advanced Practice Providers Role Growing in Oncology
The number of nurse practitioners and physician assistants in oncology is growing, according to a new study.
NCCN Issues Gestational Trophoblastic Neoplasia Guidelines
The guidelines will better ensure pregnant cancer patients receive life-saving treatment while preserving fertility.
How Does Treatment Affect the Sexuality of Head and Neck Cancer Patients?
For patients undergoing primary treatment for head and neck cancer, sexuality was significantly impacted in many patients both prior to and during cancer treatment.
Detection of Cancer Through Exhaled Breath
VOC breath tests have potential, but more guidance, standardization are needed.
Can Preoperative Oral Care Reduce Complications From Cancer Surgery?
A retrospective study shows that undergoing oral care prior to cancer surgery decreased postoperative complications.
Antidepressant Use in Cancer Patients May Affect Length of Hospital Stay
Cancer patients with a documented history of depressive symptoms prior to hospital admission experience an extended hospital stay.
Magnetic Drug Targeting May Help Reach CNS Tumors
Targeted delivery of nanoparticles may reduce systemic and CNS toxicity in spinal cord tumors.
Using Targeted Deep Sequencing to Detect ctDNA in Pancreatic Cancer
Study shows that ctDNA levels measured by targeted deep sequencing sensitively indicate the presence of cancer.