An overview of the design and rationale for the phase 2 BRIDGET study looking at the addition of tucatinib to HER2-directed antibody therapy in breast cancer.
Elacestrant Combo Shows Activity, Tolerability in Metastatic Breast Cancer
Investigators report no grade 4 adverse effects among patients who received elacestrant/abemaciclib in the phase 1b/2 ELECTRA trial.
Applying Updated Breast Cancer Findings From ASCO to Clinical Practice
Neil M. Iyengar, MD, and Paolo Tarantino, MD, discuss updated data on agents such as T-DXd and abemaciclib in breast cancer presented at 2024 ASCO.
Biosignature Test May Predict Residual Risk Post-BCS/RT in HER2+ DCIS
Use of DCISionRT may open new options for tailored treatments among patients with HER2-positive ductal carcinoma in situ.
Finding a Place for Exercise Oncology in the Treatment of Breast Cancer
Neil M. Iyengar, MD, spoke about the potential impact of exercise on patient-reported outcomes in cancer and achieving work-life balance.
Hypofractionated RT After Mastectomy Is Noninferior to SOC in Breast Cancer
Hypofractionated postmastectomy radiotherapy was noninferior to standard radiation in patients who underwent a mastectomy.
Dato-DXd Misses OS End Point in TROPION-Breast01 Trial of HR+ Breast Cancer
Datopotamab deruxtecan previously showed statistically significant improvement in progression-free survival in patients with HR+, HER2-low, or HER2-negative breast cancer.