
Oncology NEWS International
- Oncology NEWS International Vol 18 No 12
- Volume 18
- Issue 12
Cetuximab plus chemo boosts surgery in advanced colon ca
Adding cetuximab (Erbitux) to neoadjuvant chemotherapy shrank tumors enough to increase the success of curative surgery in colon cancer patients with inoperable metastatic liver lesions, according to the CELIM trial conducted in Germany and Austria.
Adding cetuximab (Erbitux) to neoadjuvant chemotherapy shrank tumors enough to increase the success of curative surgery in colon cancer patients with inoperable metastatic liver lesions, according to the CELIM trial conducted in Germany and Austria.
Patients were randomized to cetuximab treatment with FOLFOX6 or with FOLFIRI. Treatment with cetuximab resulted in high tumor response rates and a 28% increase in the proportion of tumors that were amenable to surgery. Ultimately, surgery was achieved in 34% of the patients. Because of cetuximab treatment, 60% of tumors were deemed resectable vs 32% at the start of the study (Lancet Oncology online, November 24, 2009).
Articles in this issue
almost 17 years ago
OB/GYN revises suggested age for cervical ca screeningalmost 17 years ago
Brain tumor gene mapping project launches in Seattlealmost 17 years ago
PET timing guides radiation RX in lung caalmost 17 years ago
Experts take umbrage with federal panel change to age for mammo screeningalmost 17 years ago
Radiosurgery gains role for noncancer applicationsalmost 17 years ago
New radiotracer shows early treatment response for patients with lung canceralmost 17 years ago
Addition of rituximab improves OS in chronic lymphocytic leukemiaalmost 17 years ago
Micromet scores multiple development dealsalmost 17 years ago
New agents for lymphoma take center stagealmost 17 years ago
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