Combating Endocrine Resistance in Breast Cancer With Novel Agents, Combinations

January 12, 2018

This video reviews endocrine resistance mediated by CDK4/6, FGFR, and PI3K in HR-positive breast cancer, and highlights the latest efforts to inhibit these pathways with novel targeted drugs and combinations.

In this video, Steffi Oesterreich, PhD, of the University of Pittsburgh Cancer Institute in Pennsylvania, reviews endocrine resistance mediated by CDK4/6, FGFR, and PI3K in hormone receptor (HR)-positive breast cancer, and highlights the latest efforts to inhibit these pathways with novel targeted drugs and combinations.

Oesterreich chaired a spotlight session on this topic at the 2017 San Antonio Breast Cancer Symposium (SABCS).