
Opinion|Videos|April 4, 2025
Considerations for Combinations Beyond Progression in Upper GI Cancer
Experts discuss how microsatellite-stable (MSS) status in this case affects the expected benefit of pembrolizumab and whether its continued use beyond progression in combination with other agents would be considered.
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Video content above is prompted by the following:
- How does the MSS status in this case affect the expected benefit of pembrolizumab, and would you consider its continued use beyond progression in combination with other agents?
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The phase 3 EXCALIBER-RRMM trial supports iberdomide plus daratumumab and dexamethasone as a new standard of care in relapsed/refractory multiple myeloma.

C. Ola Landgren, MD, PhD, discusses disparities in myeloma care access between academic and community practices and how his center works to bridge that gap.

Hans C. Lee, MD, discussed how he monitors patients with multiple myeloma who achieve deep, sustained MRD negativity after coming off therapy.

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