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Opinion|Videos|February 7, 2025

Data and Expert Considerations Supporting Cilta-cel as Second-Line Treatment for Robert

This video episode explores treatment decisions for second-line therapy in a patient with age and comorbidities, reviews cilta-cel data from the CARTITUDE trials, and discusses clinical experience with cilta-cel, emphasizing efficacy, quality of life, and adaptations for complex patient profiles.

Episodes in this series

EP. 1 Meet Sarah, a 55-year-old Businesswoman With Multiple Myeloma Considering CAR-T Therapy With Ide-cel

EP. 1 Meet Sarah, a 55-year-old Businesswoman With Multiple Myeloma Considering CAR-T Therapy With Ide-cel

EP. 2 Clinical Decision Making in Multiple Myeloma: CAR-T in the 2nd Line Treatment Setting

EP. 2 Clinical Decision Making in Multiple Myeloma: CAR-T in the 2nd Line Treatment Setting

EP. 3 Ide-cel vs. Cilta-cel: Tailoring CAR T in Myeloma

EP. 3 Ide-cel vs. Cilta-cel: Tailoring CAR T in Myeloma

4 experts are featured in this series.

EP. 4 Sarah’s Journey Through CAR-T Therapy: Pre-, Peri-, and Post-Treatment Considerations with Ide-cel

4 experts are featured in this series.

EP. 5 Getting to Know Robert, a 72-Year-Old Retired Teacher Facing a Myeloma Relapse and Considering CAR-T Therapy with Cilta-cel

4 experts are featured in this series.

EP. 6 Data and Expert Considerations Supporting Cilta-cel as Second-Line Treatment for Robert

4 experts are featured in this series.

EP. 7 Strategic Choices in CAR T for Myeloma: Balancing Efficacy, Safety, and BCMA vs. GPRC5D Options

Video content above is prompted by the following:

Considering Robert's age and comorbidities, what factors influence your treatment decision for second-line therapy?
- What other second-line options would you consider, and why? How do you approach the decision between CAR-T therapy and other novel agents in the second-line setting?
Let's review the data supporting cilta-cel in the second-line setting?
- What key findings from the CARTITUDE trials inform your decision to use cilta-cel in second-line treatment?
- How do these results compare to other second-line options for multiple myeloma in this patient population?
Discuss your experience using cilta-cel in the second-line setting:
- What benefits have you observed in terms of efficacy and quality of life across different patient groups?
- Are there any specific considerations or adaptations you make when treating patients with comorbidities like Robert's?

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