Epidermal Growth Factor Receptor Inhibitor Cutaneous Side Effects

October 27, 2015

This slide show highlights some of the cutaneous side effects related to the use of epidermal growth factor receptor inhibitors (EGFRI).

References:

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  • Galimont-Collen AFS, Vos LE, Lavrijsen APM, Ouwerkerk J, Gelderblom H. (2007). Classification and management of skin, hair, nail and mucosal side-effects of epidermal growth factor receptor (EGFR) inhibitors. Eur J Cancer, Mar;43(5): 845–51.
  • Cohen PR, Escudier SM, Kurzrock R. (2011). Cetuximab-associated elongation of the eyelashes: case report and review of eyelash trichomegaly secondary to epidermal growth factor receptor inhibitors. Am J Clin Dermatol., Feb 1;12(1): 63–7.
  • Pongpudpunth M, Demierre MF, Goldberg LJ. (2009). A case report of inflammatory nonscarring alopecia associated with the epidermal growth factor receptor inhibitor erlotinib. J Cutan Pathol. 2009 Dec;36(12): 1303–7.
  • Yang BH, Bang CY, Byun JW, et al. (2011). A Case of Cicatricial Alopecia Associated with Erlotinib. Ann Dermatol., Dec;23(Suppl 3): S350–353.
  • Lacouture ME, Anadkat MJ, Bensadoun RJ, et al. (2011). Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities. Support Care Cancer, Aug;19(8): 1079–95.
  • Li T, Perez-Soler R. (2009). Skin toxicities associated with epidermal growth factor receptor inhibitors. Target Oncol., Apr;4(2): 107–19.
  • Robert C, Sibaud V, Mateus C, et al. (2015). Nail toxicities induced by systemic anticancer treatments. Lancet Oncol., Apr;16(4): e181–9.
  • Tejwani A, Wu S, Jia Y, et al. (2009). Increased risk of high-grade dermatologic toxicities with radiation plus epidermal growth factor receptor inhibitor therapy. Cancer, Mar 15;115(6): 1286–99.
  • Agero AL, Dusza SW, Benvenuto-Andrade C, et al. (2006). Dermatologic side effects associated with the epidermal growth factor receptor inhibitors. J Am Acad Dermatol., Oct;55(4): 657–70.