Treatment Strategies for Managing Hepatotoxicity and Brain Metastases in KRAS G12C-Mutated NSCLC : Episode 4

KRYSTAL-7: Efficacy and Safety of Adagrasib with Pembrolizumab in Patients With Advanced KRASG12C Mutated NSCLC

December 14, 2023

Opinion

Video

KRYSTAL-7 is a study exploring the efficacy of adding adagrasib to first-line pembrolizumab in patient with NSCLC with varying PD-L1 expression levels, showing promising response rates and progression-free survival, but also adverse events like hepatotoxicity.

EP: 1.Current Treatment Landscape for KRASG12C-Mutated NSCLC

EP: 2.Treatment Options for KRASG12C Mutated NSCLC

EP: 3.KRYSTAL-1: Follow-Up Data on Adagrasib Monotherapy in Patients with Advanced/Metastatic KRASG12C Mutated NSCLC

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EP: 4.KRYSTAL-7: Efficacy and Safety of Adagrasib with Pembrolizumab in Patients With Advanced KRASG12C Mutated NSCLC

EP: 5.Long-Term Outcomes of Sotorasib Efficacy in Patients With KRASG12C Mutated NSCLC

EP: 6.Hepatotoxicity with KRASG12C Inhibitors in NSCLC

EP: 7.Sotorasib Versus Docetaxel for Previously Treated Patients With KRASG12C Mutated NSCLC: Data From CodeBreaK 200

EP: 8.Managing CNS Metastases in KRASG12C Mutated NSCLC

EP: 9.Future Directions in KRASG12C Mutated NSCLC

EP: 10.Experts Examine the Need for Targeted Therapy Options for KRAS G12C–Mutated NSCLC

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