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Opinion|Videos|December 15, 2023

KRYSTAL-1: Follow-Up Data on Adagrasib Monotherapy in Patients with Advanced/Metastatic KRASG12C Mutated NSCLC

Author(s)Narjust Florez, MD

Dr Narjust Florez discusses the KRYSTAL-1 trial, focusing on the effectiveness and side effects of adagrasib in treating patients with NSCLC and KRASG12C mutations, and noting their impact on progression-free and overall survival.

Episodes in this series

EP. 1 Current Treatment Landscape for KRASG12C-Mutated NSCLC

EP. 1 Current Treatment Landscape for KRASG12C-Mutated NSCLC

EP. 2 Treatment Options for KRASG12C Mutated NSCLC

EP. 2 Treatment Options for KRASG12C Mutated NSCLC

EP. 3 KRYSTAL-1: Follow-Up Data on Adagrasib Monotherapy in Patients with Advanced/Metastatic KRASG12C Mutated NSCLC

EP. 3 KRYSTAL-1: Follow-Up Data on Adagrasib Monotherapy in Patients with Advanced/Metastatic KRASG12C Mutated NSCLC

EP. 4 KRYSTAL-7: Efficacy and Safety of Adagrasib with Pembrolizumab in Patients With Advanced KRASG12C Mutated NSCLC

EP. 4 KRYSTAL-7: Efficacy and Safety of Adagrasib with Pembrolizumab in Patients With Advanced KRASG12C Mutated NSCLC

EP. 5 Long-Term Outcomes of Sotorasib Efficacy in Patients With KRASG12C Mutated NSCLC

EP. 5 Long-Term Outcomes of Sotorasib Efficacy in Patients With KRASG12C Mutated NSCLC

EP. 6 Hepatotoxicity with KRASG12C Inhibitors in NSCLC

EP. 6 Hepatotoxicity with KRASG12C Inhibitors in NSCLC

EP. 7 Sotorasib Versus Docetaxel for Previously Treated Patients With KRASG12C Mutated NSCLC: Data From CodeBreaK 200

EP. 7 Sotorasib Versus Docetaxel for Previously Treated Patients With KRASG12C Mutated NSCLC: Data From CodeBreaK 200

EP. 8 Managing CNS Metastases in KRASG12C Mutated NSCLC

EP. 8 Managing CNS Metastases in KRASG12C Mutated NSCLC

EP. 9 Future Directions in KRASG12C Mutated NSCLC

EP. 9 Future Directions in KRASG12C Mutated NSCLC

EP. 10 Experts Examine the Need for Targeted Therapy Options for KRAS G12C–Mutated NSCLC

EP. 10 Experts Examine the Need for Targeted Therapy Options for KRAS G12C–Mutated NSCLC

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Tiffany A. Traina, MD, FASCO; Nour Abuhadra, MD; Joshua Z. Drago, MD, MS; Ruth O’Regan, MD; Vered Stearns, MD, FASCO; Neil Vasan, MD, PhD; Anna Weiss, MD

Personalized Approaches in NSCLC: Early Detection, Molecular Testing, and Targeted Therapies

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21st Annual New York Lung Cancers Symposium®

In-Person Event

21st Annual New York Lung Cancers Symposium®

November 14, 2026

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