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|Articles|August 1, 1999

Oncology NEWS International

  • Oncology NEWS International Vol 8 No 8
  • Volume 8
  • Issue 8

NCI Discovers Gene Variations From Existing Databases

BETHESDA, Md-Using new computer software to “mine” existing databases, National Cancer Institute (NCI) scientists have discovered 10,435 possible new variations in human genes. The so-called single nucleotide polymorphisms, or SNPs, must still be validated, but NCI said each of the variations met statistical confidence levels of 0.99%.

BETHESDA, Md—Using new computer software to “mine” existing databases, National Cancer Institute (NCI) scientists have discovered 10,435 possible new variations in human genes. The so-called single nucleotide polymorphisms, or SNPs, must still be validated, but NCI said each of the variations met statistical confidence levels of 0.99%.

SNPs are considered likely influences on how fast a cancer grows and how well it responds to treatment. However, finding and understanding the variations has posed a considerable technical challenge, one eased somewhat by the special software used by the NCI scientists, noted team leader Kenneth Buetow, PhD.

Information on the new SNPs is available free to researchers on the NCI’s Cancer Genome Anatomy Project website (http://lpg.nci.nih.gov).

Articles in this issue

over 16 years ago

False positives frequent in CT lung cancer screening trial

almost 27 years ago

Stereotactic Core Biopsy Establishes Many Prognostic Factors

almost 27 years ago

Breast Cancer Prevention With Tamoxifen Appears Cost-Effective

almost 27 years ago

CPDR Unveils First Center Solely for Prostate Cancer Research

almost 27 years ago

Going Beyond CHOP in Advanced Large-Cell Lymphoma

almost 27 years ago

Memorial Sloan-Kettering Opens Rockefeller Outpatient Pavilion

almost 27 years ago

Ernst Wynder, Pioneer in Preventive Medicine

almost 27 years ago

AHCPR Plans Health Care Market, Managed Care Research Centers

almost 27 years ago

NSAIDs May Protect Against Common GI Cancers

almost 27 years ago

Four Researchers Receive General Motors Awards

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