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Opinion|Videos|November 13, 2024

OPTec: Outpatient Step Up Administration of Teclistamab: Implications in Real-World Practice

Author(s)Ajai Chari, MD, Thomas G. Martin, MD, Jens Hillengass, MD, PhD

Panelists discuss how the OPTec study, which explores outpatient step-up administration of teclistamab, could impact real-world practice by potentially improving patient convenience and reducing healthcare resource utilization in the treatment of multiple myeloma.

Episodes in this series

9 Experts are featured in this series.

EP. 1 Talquetamab, a GPRC5DxCD3 bispecific antibody (BsAb), for Relapsed Refractory Multiple Myeloma: MonumenTAL-1 Data and Implications

9 Experts are featured in this series.

EP. 2 Bispecific Antibody Combinations In Relapsed Refractory Multiple Myeloma: TRIMM-2 Study

9 Experts are featured in this series.

EP. 3 Bispecific Antibody Combinations In Relapsed Refractory Multiple Myeloma: RedirecTT-1 Follow-Up

9 Experts are featured in this series.

EP. 4 Prophylactic Tocilizumab in MajesTEC-1 for the Reduction of CRS

9 Experts are featured in this series.

EP. 5 OPTec: Outpatient Step Up Administration of Teclistamab: Implications in Real-World Practice

9 Experts are featured in this series.

EP. 6 Sequencing Therapies in Relapsed Refractory Multiple Myeloma: Bispecifics and CAR T-Cell Therapies

9 Experts are featured in this series.

EP. 7 Dosing Interval and Considerations for Bispecifics Combination in Relapsed Refractory Multiple Myeloma

9 Experts are featured in this series.

EP. 8 Clinical Scenario: A 58-Year Old Woman with Relapsed Refractory Mutiple Myeloma, post-ASCT, MRD-negative, on Bispecific Therapy

9 Experts are featured in this series.

EP. 9 Clinical Scenario: Implementation of Bispecific Therapy for Relapsed Refractory Multiple Myeloma in a Community Center

EP. 10 Experts Discuss Choosing Bispecifics and Sequencing Options in Multiple Myeloma

EP. 10 Experts Discuss Choosing Bispecifics and Sequencing Options in Multiple Myeloma

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Stay up to date on recent advances in the multidisciplinary approach to cancer.

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Being able to treat patients with cevostamab who have multiple myeloma after 1 to 3 prior lines of therapy vs 4 lines may allow for better outcomes.

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$The median OS among patients with triple-class–exposed relapsed/refractory multiple myeloma with or without EMD was 12.6 months vs 36.4 months.$

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$The 6- and 12-month PFS rates were 76.4% and 68.2%, respectively, in patients with relapsed/refractory multiple myeloma who discontinued treatment with teclistamab early.$

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Current FDA expectations may allow patients to return to their community physicians at 2 weeks after administration of anitocabtagene autoleucel.

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