Prostate Cancer Death Linked With Shorter Sleep Duration

Video

This video examines results of a study that found that shorter sleep duration was linked with an increased risk of death among patients with prostate cancer.

In this video, Susan M. Gapstur, PhD, MPH, of the American Cancer Society in Atlanta, discusses an analysis of two large, long-term cohort studies-Cancer Prevention Study-I and Cancer Prevention Study-II-that found that sleep duration was linked with an increased risk of death among patients with prostate cancer.

Results of the study were presented at the 2017 American Association for Cancer Research (AACR) Annual Meeting, held April 1–5 in Washington, DC.

The biological mechanism behind this association is unclear, but research has shown that lack of sleep and the presence of light at night can affect melatonin production, and that low melatonin production can lead to an increase in genetic mutations and can limit DNA repair.

Recent Videos
Paolo Tarantino, MD discusses updated breast cancer trial findings presented at ESMO 2024 supporting the use of agents such as T-DXd and ribociclib.
Higher, durable rates of response to frontline therapy are needed to potentially improve long-term survival among patients with non–small cell lung cancer.
Although no responses were observed in 11 patients receiving abemaciclib monotherapy, combination therapies with abemaciclib may offer clinical benefit.
Findings show no difference in overall survival between various treatments for metastatic RCC previously managed with immunotherapy and TKIs.
An epigenomic profiling approach may help pick up the entire tumor burden, thereby assisting with detecting sarcomatoid features in those with RCC.
Future meetings may address how immunotherapy, bispecific agents, and CAR T-cell therapies can further impact the AML treatment paradigm.
Treatment with revumenib appeared to demonstrate efficacy among patients with KMT2A-rearranged acute leukemia in the phase 2 AUGMENT-101 study.
Advocacy groups such as Cancer Support Community and the Leukemia & Lymphoma Society may help support patients with CML undergoing treatment.
Paolo Tarantino, MD, discusses the potential utility of agents such as datopotamab deruxtecan and enfortumab vedotin in patients with breast cancer.
Related Content