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Opinion|Videos|October 3, 2024

Safety Profile of the Pelabresib and Ruxolitinib Combination in Myelofibrosis

Author(s)David M. Swoboda, MD, Andrew T. Kuykendall, MD

Panelists discuss the safety profile of the pelabresib and ruxolitinib combination in myelofibrosis.

Episodes in this series

EP. 1 Myelofibrosis: Background, Risk Stratification, and Treatment Decision-Making

EP. 1 Myelofibrosis: Background, Risk Stratification, and Treatment Decision-Making

EP. 2 Approved and Investigational Agents for Myelofibrosis

EP. 2 Approved and Investigational Agents for Myelofibrosis

EP. 3 Disease Modification Strategies and Unmet Needs in Myelofibrosis

EP. 3 Disease Modification Strategies and Unmet Needs in Myelofibrosis

EP. 4 MANIFEST-2: Pelabresib in Myelofibrosis: MOA, Study Design, and Spleen Volume Reduction

EP. 4 MANIFEST-2: Pelabresib in Myelofibrosis: MOA, Study Design, and Spleen Volume Reduction

EP. 5 Disease- Modifying Biomarker Data in the MANIFEST-2 Study Investigating Pelabresib

EP. 5 Disease- Modifying Biomarker Data in the MANIFEST-2 Study Investigating Pelabresib

EP. 6 Safety Profile of the Pelabresib and Ruxolitinib Combination in Myelofibrosis

EP. 7 Pelabresib in MPNs: Immune Profiles of Responders vs. Non-responders

EP. 7 Pelabresib in MPNs: Immune Profiles of Responders vs. Non-responders

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Stay up to date on recent advances in the multidisciplinary approach to cancer.

Latest CME

Antibody–Drug Conjugates in Oncology: The Essentials of AE Management for Better Patient Outcomes

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Antibody–Drug Conjugates in Oncology: The Essentials of AE Management for Better Patient Outcomes

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(COPE) Optimizing Management of Ocular Toxicity in Cancer Patients: The Role of Ophthalmologists in the Spectrum of Care

(COPE) Optimizing Management of Ocular Toxicity in Cancer Patients: The Role of Ophthalmologists in the Spectrum of Care

Asim V. Farooq, MD; Joann Kang, MD; Nita Lee, MD, MPH

(CME) Optimizing Management of Ocular Toxicity in Cancer Patients: The Role of Ophthalmologists in the Spectrum of Care

(CME) Optimizing Management of Ocular Toxicity in Cancer Patients: The Role of Ophthalmologists in the Spectrum of Care

Asim V. Farooq, MD; Joann Kang, MD; Nita Lee, MD, MPH

Community Oncology Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy – Strategies for the Multidisciplinary Team | Iowa

Community Oncology Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy – Strategies for the Multidisciplinary Team | Iowa

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Community Oncology Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy – Strategies for the Multidisciplinary Team | New York

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Yana G. Najjar, MD; Deepa Jagtap, MD

Community Oncology Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy – Strategies for the Multidisciplinary Team | Minnesota

Community Oncology Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy – Strategies for the Multidisciplinary Team | Minnesota

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20th Annual New York Lung Cancers Symposium®

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20th Annual New York Lung Cancers Symposium®

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Community Oncology Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy – Strategies for the Multidisciplinary Team | Texas

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Community Oncology Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy – Strategies for the Multidisciplinary Team | Washington

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Advances In™: Taking R/R B-Cell ALL Management to the Next Level With New CAR T Approval

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Burst CME™: Implementing Appropriate Recognition and Diagnosis of Low-Grade Serous Ovarian Cancer

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Burst CME™: Understanding Novel Advances in LGSOC—A Focus on New Mechanisms of Action and Clinical Trials

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In-Person + Virtual Event

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Vinay K. Puduvalli, MD; Manmeet Ahluwalia, MD, MBA; Stephen J. Bagley, MD, MSCE; Angela Waanders, MD, MPH, MS

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Joyce O’Shaughnessy, MD; Matthew P. Goetz, MD; Hope S. Rugo, MD, FASCO

Expert Guidance on Frequently Asked Questions Regarding the Use of ADCs in TNBC

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Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD; Virginia Kaklamani, MD, DSc

Evaluating the Latest Data and Ongoing Trials for Novel ADC Approaches in TNBC

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Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD

Establishing the Rationale for ADC and ICI Combinations in TNBC

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Virginia Kaklamani, MD, DSc; Tiffany A. Traina, MD, FASCO

Breaking Down the Rationale for Targeting TROP2 in TNBC

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Filipa Lynce, MD; Rita Nanda, MD

Dissecting Clinical Trial and Real-World Data for ADCs in TNBC

Dissecting Clinical Trial and Real-World Data for ADCs in TNBC

Filipa Lynce, MD; Rita Nanda, MD

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Rahul Gosain, MD, MBA; Rohit Gosain, MD; Hossein Borghaei, DO, MS

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Ghassan Abou-Alfa, MD, MBA; Laura Williams Goff, MD, MSCI, MMHC, FASCO; Arndt Vogel, MD, PhD

Cross-Disease Integration of Immunotherapy Innovations

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Ghassan Abou-Alfa, MD, MBA; Laura Williams Goff, MD, MSCI, MMHC, FASCO; Arndt Vogel, MD, PhD

Broadening the Frontline—Studies Informing the Use of Immunotherapy in Hepatocellular Carcinoma

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Ghassan Abou-Alfa, MD, MBA; Laura Williams Goff, MD, MSCI, MMHC, FASCO; Arndt Vogel, MD, PhD

PER Resource Center: Integrating Novel Approaches in TNBC – New Avenues for TROP2-Targeting ADCs and Beyond – Nursing

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Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD; Virginia Kaklamani, MD, DSc; Filipa Lynce, MD; Rita Nanda, MD; Tiffany A. Traina, MD, FASCO

Show Me the Data®: New and Emerging Roles for Oral SERD Therapy in the Treatment of ER+/HER2– Breast Cancer

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Expert Roundtable and Panel Discussions: Current and Future Landscape of TNBC

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Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD; Tiffany A. Traina, MD, FASCO

Practical Considerations and Future Directions for New Treatment Strategies in SCLC

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Radioligand Therapy 101: The Science Behind the Strategy

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Ready for Radioligand Therapy? Patient Selection and Sequencing Simplified

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Jeremie Calais, MD, PhD; Tanya B. Dorff, MD; Scott T. Tagawa, MD, MS, FACP, FASCO

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Advances in Managing EGFR-Mutant NSCLC: Applying Evidence Across the Disease Continuum

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Enhancing Prostate Cancer Outcomes – The Role of PSMA and Targeted Treatment Strategies

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Medical Crossfire® in Adjunctive Testing: Charting a New Course in Prostate Cancer Risk Assessment

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