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News|Videos|January 20, 2023

Selecting the Appropriate BTK Inhibitor for Frontline Treatment of CLL

Author(s)Susan O'Brien, MD, Alexey Danilov, MD, PhD, Seema Ali Bhat, MD

Catherine Coombs, MD, reviews data on BTK inhibitors ibrutinib, acalabrutinib, and zanubrutinib in the first-line treatment of CLL, and how she approaches selecting the appropriate BTK inhibitor in practice.

Episodes in this series

EP. 1 Mechanism of Action of BTK Inhibitors in Chronic Lymphocytic Leukemia

EP. 1 Mechanism of Action of BTK Inhibitors in Chronic Lymphocytic Leukemia

EP. 2 Selecting the Appropriate BTK Inhibitor for Frontline Treatment of CLL

EP. 2 Selecting the Appropriate BTK Inhibitor for Frontline Treatment of CLL

EP. 3 BTK Inhibitors for the Treatment of Relapsed CLL

EP. 3 BTK Inhibitors for the Treatment of Relapsed CLL

EP. 4 Comparing BTK Inhibitors in the Treatment of Relapsed CLL

EP. 4 Comparing BTK Inhibitors in the Treatment of Relapsed CLL

EP. 5 Selecting an Appropriate BTK Inhibitor for the Treatment of Relapsed CLL

EP. 5 Selecting an Appropriate BTK Inhibitor for the Treatment of Relapsed CLL

EP. 6 Non-Covalent BTK Inhibitors in the Treatment of CLL: Pirtobrutinib

EP. 6 Non-Covalent BTK Inhibitors in the Treatment of CLL: Pirtobrutinib

EP. 7 Non-Covalent BTK Inhibitors in the Treatment of CLL: Nemtabrutinib

EP. 7 Non-Covalent BTK Inhibitors in the Treatment of CLL: Nemtabrutinib

EP. 8 Fixed-Duration Venetoclax in the Treatment of CLL

EP. 8 Fixed-Duration Venetoclax in the Treatment of CLL

EP. 9 Role of Venetoclax in Patients with High-Risk CLL

EP. 9 Role of Venetoclax in Patients with High-Risk CLL

EP. 10 Sequencing Therapies in CLL

EP. 10 Sequencing Therapies in CLL

EP. 11 Emerging Therapies in CLL

EP. 11 Emerging Therapies in CLL

EP. 12 Unmet Needs and Future Perspectives in the Treatment of CLL

EP. 12 Unmet Needs and Future Perspectives in the Treatment of CLL

Recap: BTK Inhibition and Treatment Options in Chronic Lymphocytic Leukemia

EP. 13 Recap: BTK Inhibition and Treatment Options in Chronic Lymphocytic Leukemia

Newsletter

Stay up to date on recent advances in the multidisciplinary approach to cancer.

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Those with TP53-mutated disease may benefit from continuous BTK inhibitor therapy, although limited-duration therapy is worthy of discussion.

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