Study to Measure Impact of ProstaScint Imaging in Prostate Cancer

Publication
Article
Oncology NEWS InternationalOncology NEWS International Vol 11 No 7
Volume 11
Issue 7

PRINCETON, New Jersey-Cytogen Corporation’s ProstaScint (capromab pendetide) is being evaluated in a phase I/II clinical study for its utility in helping guide intensity modulated radiation therapy (IMRT) for prostate cancer.

PRINCETON, New Jersey—Cytogen Corporation’s ProstaScint (capromabpendetide) is being evaluated in a phase I/II clinical study for its utility inhelping guide intensity modulated radiation therapy (IMRT) for prostate cancer. 

ProstaScint is a radiolabeled monoclonal antibody that targets prostate specificmembrane antigen. In the study, the specific areas of greatest tumor burdenwithin the prostate, identified by the ProstaScint image, will receive boosteddoses of radiation via IMRT.

Articles in this issue
Translational Research, Early Clinical Trials Support Xeloda/RT in GI Cancers
Capecitabine Research Points to New Combinations for Metastatic Breast Cancer
Good Activity for Capecitabine Confirmed in European Study
European Data Support Benefit of Capecitabine/Irinotecan Regimen in Advanced Colorectal Cancer Patients
Single-Agent Capecitabine May Benefit Elderly Colorectal Cancer Patients
Single-Agent Sequential Rx May Be Reasonable for Metastatic Breast Cancer
Intermittent R115777 Equally Effective but Better Tolerated in Breast Cancer Patients
Carboplatin/Vinorelbine/Capecitabine Active in Pretreated Metastatic Breast Cancer
Longer Survival With FOLFOX4 in Metastatic Colorectal Cancer Patients
Capecitabine/Vinorelbine Effective in Heavily Pretreated Patients
Oral Regimen of UFT/Leucovorin and Etoposide Shows Promising Results
Docetaxel/Capecitabine Bests Single-Agent Docetaxel in Metastatic Breast Cancer
COX-2 Inhibitor May Boost Capecitabine Response
Celecoxib Added to IFL Reduces Toxicity in Patients With Metastatic Colorectal Cancer
Irinotecan Every 2 Weeks With Capecitabine Is Well Tolerated
Recent Videos
A phase 1 trial assessed the use of PSCA-directed CAR T cells in patients with metastatic castration-resistant prostate cancer.
Findings from a phase 1 study may inform future trial designs intended to yield longer responses with PSCA-targeted CAR T cells.
A phase 1 trial assessed the use of PSCA-directed CAR T cells in patients with metastatic castration-resistant prostate cancer.
Ongoing research may clarify the potential benefit of avelumab when administered in combination with other agents in advanced urothelial carcinoma.
Spatial analyses may help determine factors that influence responses to sacituzumab govitecan-containing regimens in urothelial carcinoma.
Attending educational sessions may help with understanding how to manage toxicities associated with enfortumab vedotin in rare genitourinary cancers.
Two women in genitourinary oncology discuss their experiences with figuring out when to begin a family and how to prioritize both work and children.
Over the past few decades, the prostate cancer space has evolved with increased funding for clinical trial creation and enrollment.
Related Content
A combined genomic and histological analysis within trial datasets demonstrates a sound tumor evaluation strategy for patients with prostate cancer.

Tool Combining Genomics, AI May Predict Future Prostate Cancer Recurrence

Roman Fabbricatore
July 23rd 2024
Article

A combined genomic and histological analysis within trial datasets demonstrates a sound tumor evaluation strategy for patients with prostate cancer.

AI tools may show utility in areas such as prostate diagnostic imaging, pathology, and treatment outcome predictions.

Leveraging Artificial Intelligence Evolutions in Prostate Cancer Care

James B. Yu, MD, MHS, FASTRO;Julian C. Hong, MD, MS
July 1st 2024
Podcast

AI tools may show utility in areas such as prostate diagnostic imaging, pathology, and treatment outcome predictions.

Developers plan to submit data from the ARANOTE trial to global regulatory health authorities to expand indications for darolutamide in metastatic HSPC.

Darolutamide Combo Improves Radiological PFS in Metastatic HSPC

Russ Conroy
July 17th 2024
Article

Developers plan to submit data from the ARANOTE trial to global regulatory health authorities to expand indications for darolutamide in metastatic HSPC.

Leaders in genitourinary oncology spoke about key research advances as well as personal experiences in navigating the field.

Finding Ways to Break the Mold in GU Oncology

Maha H. Hussain, MD;Sarah E. Fenton, MD, PhD
April 8th 2024
Podcast

Leaders in genitourinary oncology spoke about key research advances as well as personal experiences in navigating the field.

In a phase 1 trial, City of Hope’s CAR T-cell therapy showed minimal adverse effects and promising therapeutic activity for advanced prostate cancer.

CAR T-Cell Therapy Demonstrates Promising Results for mCRPC

Roman Fabbricatore
June 27th 2024
Article

In a phase 1 trial, City of Hope’s CAR T-cell therapy showed minimal adverse effects and promising therapeutic activity for advanced prostate cancer.

Compared with cognitively-defined and hemigland contours, AI-assisted cancer contours delivered a greater balanced accuracy rate.

AI-Assisted Contours Exhibit High Accuracy in Evaluating Prostate Cancer

Roman Fabbricatore
June 20th 2024
Article

Compared with cognitively-defined and hemigland contours, AI-assisted cancer contours delivered a greater balanced accuracy rate.