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Your AI-Trained Oncology Knowledge Connection!

Opinion|Videos|August 1, 2025

When Melanoma Spreads to the Brain: Michael’s Story

Author(s)Michael A. Postow, MD, Evan J. Lipson, MD, Hussein Abdul-Hassan Tawbi, MD, PhD

This is an actor portrayal of a hypothetical patient profile developed for educational purposes based on characteristics of patients with multiple myeloma as seen in clinical practice. The hypothetical case was co-developed by staff medical writers with Cancer Network/ONN.”

Episodes in this series

EP. 1 RELATIVITY-047 4-Year Update: Long-Term Outcomes in Frontline Metastatic Melanoma

EP. 1 RELATIVITY-047 4-Year Update: Long-Term Outcomes in Frontline Metastatic Melanoma

EP. 2 Case Study: Sarah’s Journey With High-Burden BRAF V600E Melanoma

EP. 2 Case Study: Sarah’s Journey With High-Burden BRAF V600E Melanoma

EP. 3 RELATIVITY-047 at 4 Years: What Long-Term Data Mean for Sarah’s Treatment Options

EP. 3 RELATIVITY-047 at 4 Years: What Long-Term Data Mean for Sarah’s Treatment Options

EP. 4 Nivo-Rela vs Nivo-Ipi: What 4-Year ITC and Real-World Data Tell Us About Treatment Selection

EP. 4 Nivo-Rela vs Nivo-Ipi: What 4-Year ITC and Real-World Data Tell Us About Treatment Selection

EP. 5 Patient Support Strategies in Metastatic Melanoma: Multidisciplinary Perspectives

EP. 5 Patient Support Strategies in Metastatic Melanoma: Multidisciplinary Perspectives

EP. 6 When Melanoma Spreads to the Brain: Michael’s Story

EP. 6 When Melanoma Spreads to the Brain: Michael’s Story

EP. 7 Managing Complexity: Care Coordination for CNS Metastases

EP. 7 Managing Complexity: Care Coordination for CNS Metastases

EP. 8 Immunotherapy for CNS Melanoma: RELATIVITY-020’s Intracranial Efficacy Data

EP. 8 Immunotherapy for CNS Melanoma: RELATIVITY-020’s Intracranial Efficacy Data

EP. 9 When is Nivolumab/Relatlimab Therapy Viable in BRAF+ Melanoma?

EP. 9 When is Nivolumab/Relatlimab Therapy Viable in BRAF+ Melanoma?

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Establishing the Rationale for ADC and ICI Combinations in TNBC

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Dissecting Clinical Trial and Real-World Data for ADCs in TNBC

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Breaking Down the Rationale for Targeting TROP2 in TNBC

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Optimizing Treatment for Biliary Tract Cancers

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Broadening the Frontline—Studies Informing the Use of Immunotherapy in Hepatocellular Carcinoma

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Cross-Disease Integration of Immunotherapy Innovations

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Expert Roundtable and Panel Discussions: Current and Future Landscape of TNBC

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Show Me the Data®: New and Emerging Roles for Oral SERD Therapy in the Treatment of ER+/HER2– Breast Cancer

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Ana C. Garrido-Castro, MD; Pedram Razavi, MD, PhD

Practical Considerations and Future Directions for New Treatment Strategies in SCLC

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PER Resource Center: Integrating Novel Approaches in TNBC – New Avenues for TROP2-Targeting ADCs and Beyond – Nursing

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Radioligand Therapy 101: The Science Behind the Strategy

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Jeremie Calais, MD, PhD; Tanya B. Dorff, MD; Scott T. Tagawa, MD, MS, FACP, FASCO

Working Together: Overcoming Barriers to Optimize Outcomes in Patients Treated With Radioligand Therapy Through Multidisciplinary Care

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21st Annual New York Lung Cancers Symposium®

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Community Practice Connections™: Optimizing SCLC Treatment Strategies and Managing Adverse Events Across Disease Stages

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Erminia Massarelli, MD, PhD, MS; Misty D. Shields, MD, PhD

Navigating the Adverse Event Landscape in HER2+ GEA Therapy

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Medical Crossfire® in Adjunctive Testing: Charting a New Course in Prostate Cancer Risk Assessment

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Jason Hafron, MD; Aaron D. Berger, MD; Arpeet Shah, MD

Community Practice Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy–Strategies for the Multidisciplinary Team

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Yana G. Najjar, MD; Sapna Patel, MD

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