20 On the Upswing: A Retrospective Cohort Study Evaluating Neoadjuvant Chemotherapy Response in Metaplastic Breast Cancer Patients
ByJessica F. Moore,Victoria Tiedemann,Julia Rozenberg,I. Angeles,Kamaljeet Singh,Stephanie Ng,Ashley R. Stuckey,Micaela A. Weaver,Jennifer Gass,William M. Sikov, MD,David A. Edmonson In 21 patients with metaplastic breast cancer receiving neoadjuvant chemotherapy, 48% achieved pCR—higher than prior estimates—with all pCR patients alive and disease-free at follow-up, suggesting modern regimens including pembrolizumab may improve outcomes in this chemoresistant subtype.