Author | Timothy M. Kuzel, MD

Articles

Primary Cutaneous CD30+ Lymphoproliferative Disorders: New Insights Into Biology and Therapy

April 30, 2007

ByChristiane Querfeld, MD, PhD|Timothy M. Kuzel, MD|Joan Guitart, MD|Steven T. Rosen, MD

The spectrum of CD30+ lymphoproliferative diseases of the skin includes CD30+ cutaneous anaplastic large cell lymphoma, lymphomatoid papulosis, as well as borderline cases. These entities constitute the second most common group of cutaneous lymphomas according to the newly revised World Health Organization and European Organisation for Research and Treatment of Cancer consensus classification. Recent progress in immune and molecular biology, and identification of therapeutic targets have increased our understanding of these diseases and have led to novel treatment approaches. This review will provide an update on recent findings of immunologic, molecular, cytogenetic features and treatment strategies for patients with CD30+ lympho-proliferative diseases.

Cutaneous T-Cell Lymphoma: Pathogenesis and Treatment

July 01, 2000

ByTimothy M. Kuzel, MD|Steven T. Rosen, MD

Drs. Girardi and Edelson provide a concise discussion of current issues surrounding the management of patients with cutaneous T-cell lymphomas. They discuss a number of current theories regarding etiology and pathogenesis and provide a

Commentary (Rosen et al): Early Detection of Cutaneous Lymphoma

October 01, 1998

BySteven T. Rosen, MD|Joan Guitart, MD|Timothy M. Kuzel, MD

Cutaneous lymphomas comprise a spectrum of diseases characterized by infiltration of the skin by malignant lymphocytes. The clinical manifestations of cutaneous lymphomas vary, and they can mimic benign dermatoses,