scout

Breast Cancer

Latest News


CME Content


HOUSTON--More than half of the patients who present to M.D. Anderson Cancer Center’s emergency room have a complaint of dyspnea, Sandra Henke, RN, a thoracic oncology nurse at M.D. Anderson, said at the Center’s 2nd Annual Nursing Conference. "Even when there are other emergency symptoms, breathing difficulties are the most pronounced because they cause the most distress for the patient," Ms. Henke said.

LONDON--Interim analyses of two randomized European trials of tamoxifen (Nolvadex) prophylaxis in healthy women have failed to show a significant reduction in the incidence of breast cancer, in contrast to the US Breast Cancer Prevention Trial (BCPT), which showed a 45% reduction with tamoxifen.

DALLAS--The Susan G. Komen Breast Cancer Foundation has announced the recipients of its 1998 postdoctoral fellowship grants, which total more than $1 million. In addition to these 10 new first-year grant recipients, the Komen Foundation currently funds 21 previously awarded fellowships throughout the United States.

LOS ANGELES--Avon’s Breast Cancer 3-Day is a new type of fundraising event--the first-ever multiday long distance walk. On October 23, 24, and 25, 1998, nearly 2,000 people in California will walk 50 to 60 miles (15 to 25 miles a day), beginning just south of Santa Barbara and ending just north of Malibu. Each participant has pledged to raise a minimum of $1,700 to support breast cancer awareness and education.

ATLANTA--The American Cancer Society is offering a "magalog," part magazine, part catalog, for women recovering from breast cancer and other cancers that involve treatment-related hair loss. Known as tlc (tender loving care), the nonprofit publication was created by Lana Leavitt Rosenfeld, an ACS volunteer.

PHILADELPHIA--The NCCN (National Comprehensive Cancer Network) has received a $1 million unrestricted grant from Genentech, Inc. The grant, provided over a 2-year period, will be used to support the development and expansion of the NCCN Oncology Outcomes Database with emphasis on breast cancer and non-Hodgkin’s lymphoma.

LOS ANGELES--For patients with refractory metastatic breast cancer, ideal therapy would offer palliation with ease of administration and limited side effects. The new agent capecitabine (Xeloda) can be taken orally at home, making it unique among currently available salvage regimens for metastatic breast cancer, Joanne L. Blum, MD, PhD, of Texas Oncology, Dallas, said at the 34th Annual Meeting of the American Society of Clinical Oncology (ASCO).

WASHINGTON--The FDA’s On-cology Drugs Advisory Committee (ODAC) has recommended full approval of Rhône-Poulenc Rorer’s Taxotere (docetaxel) and a widening of the advanced breast cancer indication that received conditional approval in 1996, subject to completion of phase III trials.

MILAN, Italy--Concern about the cardiotoxicity reported in early studies of AT--doxorubicin (Adriamycin)/paclitaxel (Taxol)--in advanced breast cancer was somewhat eased by a retrospective analysis of all previous AT studies.

LOS ANGELES--A monoclonal antibody directed at the HER2 receptor greatly enhances the effect of chemotherapy for women whose breast cancer overexpresses the HER2 gene. This encouraging finding comes as experts are beginning to suspect that increasing dose intensity of conventional chemotherapy may have "gone about as far as it can go," said Dennis Slamon, MD, PhD, chief, Division of Hematology-Oncology, UCLA School of Medicine.

SAN FRANCISCO--Raloxifene (Evista), an estrogen-receptor modulator used to treat osteoporosis, also has a protective effect against breast cancer, according to a 2-year randomized study and an overview analysis reported at ASCO. These findings require some caution in interpretation, since they were mainly observed in women with osteoporosis, a population that has a lower breast cancer risk than the general population.

SAN FRANCISCO--Interim results of a major intergroup study of paclitaxel (Taxol) as adjuvant treatment of node-positive breast cancer "will change the standard of care for node-positive breast cancer patients," I. Craig Henderson, MD, of the University of California, San Francisco, said at ASCO.

NEW YORK--There is a soap opera scenario surrounding breast cancer survivors that goes something like this: "Breast cancer ruins the woman’s life. Her husband leaves her for another woman. She loses her job. She considers suicide but bravely goes on, knowing no man will ever want her. Looking in the mirror is her worst nightmare."