Paclitaxel Serum Concentrations Linked to Severity of Neuropathy in Breast Cancer Patients
January 13th 2018This video highlights a study that examined whether systemic paclitaxel concentrations in breast cancer patients were associated with severity and progression of chemotherapy-induced peripheral neuropathy.
Combating Endocrine Resistance in Breast Cancer With Novel Agents, Combinations
January 12th 2018This video reviews endocrine resistance mediated by CDK4/6, FGFR, and PI3K in HR-positive breast cancer, and highlights the latest efforts to inhibit these pathways with novel targeted drugs and combinations.
Immunotherapies Could Play Role in CALR-Positive Myeloproliferative Neoplasms
December 28th 2017This video highlights a study that establishes mutated CALR as a myeloproliferative neoplasms–specific tumor antigen and provides a rationale for the development of immunotherapies targeting mutated CALR.
Identifying Children With Leukemia Predisposition Syndromes
December 25th 2017This video reviews classic syndromes associated with increased leukemia susceptibility and highlights pediatric patients who may be at increased risk for an inherited leukemia predisposition and should receive additional work-up.