Oncology Vol 33 No 4

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Regorafenib for Metastatic Colorectal Cancer: Common Toxicities and Prevention Strategies

Regorafenib for Metastatic Colorectal Cancer: Common Toxicities and Prevention Strategies

Amber Draper, PharmD, BCOP
April 15th 2019
Article

An oncology pharmacist discusses how to prevent and treat the toxicities from regorafenib for the treatment of colorectal cancer.

Multiple Myeloma With Extramedullary Disease: A Challenging Clinical Dilemma

Multiple Myeloma With Extramedullary Disease: A Challenging Clinical Dilemma

Katherinee Morales-Chacón, MD;María T. Bourlon, MD, MSc;Deborah Martínez-Baños, MD, PhD;Jesús Delgado-de-la-Mora, MD;Christianne Bourlon, MD, MHSc
April 15th 2019
Article

A 39-year-old woman with no significant medical history presented to the emergency department with progressive diffuse abdominal pain, involuntary weight loss, anemic syndrome, and limitation of mobility. What is the best treatment course to follow?

Targeted Therapy for Mutation-Driven Metastatic Non–Small-Cell Lung Cancer: Considerations for ALK-Rearranged Tumors

Targeted Therapy for Mutation-Driven Metastatic Non–Small-Cell Lung Cancer: Considerations for ALK-Rearranged Tumors

Kathryn F. Mileham, MD, FACP;Mufti N. Ahmad, MD, FACP;Edward S. Kim, MD, FACP
April 15th 2019
Article

In this article, important concepts in the molecular testing of non–small-cell lung cancer are highlighted.

Recent Clinical Trials Explore Immunotherapies for Urothelial Carcinoma

Recent Clinical Trials Explore Immunotherapies for Urothelial Carcinoma

Arjun V. Balar, MD
April 15th 2019
Article

Dr. Balar highlights promising evidence on the potential benefits of the use of immunotherapy in the advanced bladder cancer setting.

Combining Chemotherapy and Immunotherapy for the Treatment of Triple-Negative Breast Cancer

Combining Chemotherapy and Immunotherapy for the Treatment of Triple-Negative Breast Cancer

Heather McArthur, MD, MPH
April 15th 2019
Article

Dr. McArthur discusses the latest results of immunotherapy trials in the treatment of triple-negative breast cancer.

Supporting Data vs Patient Requests in Oncology: When the Two Don’t Coincide

Supporting Data vs Patient Requests in Oncology: When the Two Don’t Coincide

Mehmet Sitki Copur, MD
April 15th 2019
Article

This article reviews patient requests and how they may be in contrast with guidelines, and provides recommendations from a community oncology practice perspective.

What to Do When Anti–PD-1 Therapy Fails in Patients With Melanoma

What to Do When Anti–PD-1 Therapy Fails in Patients With Melanoma

Meghan J. Mooradian, MD;Ryan J. Sullivan, MD
April 15th 2019
Article

This review summarizes the current available treatment strategies for patients with advanced melanoma when PD-1–directed therapy is not enough.

Novel Targets and Precision Medicine for Prostate Cancer-Part 2: Tumor Profiling and Personalized Therapy in Patients With Castration-Resistant Prostate Cancer

Novel Targets and Precision Medicine for Prostate Cancer-Part 2: Tumor Profiling and Personalized Therapy in Patients With Castration-Resistant Prostate Cancer

Bryden Considine, DO;Daniel P. Petrylak, MD
April 15th 2019
Article

In this article, we review the current use of and future direction for genetic testing and tumor profiling in patients with metastatic castration-resistant prostate cancer.