News|Articles|October 1, 2024

Adaptive Radiotherapy Modality Appears Safe, Feasible in High-Grade Glioma

Author(s)Russ Conroy
Fact checked by: Ariana Pelosci

UNITED is the first trial to assess MR-guided weekly adaptive on-line and real-time radiotherapy with clinical target volume margin reductions.

Weekly on-line MR-Linac (MRL) adaptive radiotherapy plus concurrent temozolomide (Temodar) appeared safe and feasible while significantly reducing the clinical target volume (CTV) margins and normal brain tissue exposure among patients with high-grade glioma, according to findings from the phase 2 UNITED trial (NCT04726397) presented at the 2024 American Society for Radiation Oncology Annual Meeting (ASTRO).1