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Opinion|Videos|January 24, 2025

Approaches to Bridging Therapy During the CAR T Manufacturing Process

Author(s)Al-Ola Abdallah, MD, Muhammad Umair Mushtaq, MD , Jeries Kort, MD

Panelists discuss how bridging therapy during the CAR T manufacturing waiting period requires careful patient-specific decisions about whether to use chemotherapy, targeted agents, or observation alone, based on disease aggressiveness, patient condition, and expected manufacturing timeframes.

Episodes in this series

EP. 1 Clinical Perspectives: Utilizing CAR-T Therapy in R/R MM

EP. 1 Clinical Perspectives: Utilizing CAR-T Therapy in R/R MM

EP. 2 Improving CAR-T Availability and Accessibility: How Does the Earlier Use of CAR-T Impact Treatment Sequencing?

EP. 2 Improving CAR-T Availability and Accessibility: How Does the Earlier Use of CAR-T Impact Treatment Sequencing?

EP. 3 Selecting Between the Currently Available CAR-T Therapies for R/R MM: Patient Considerations and Criteria

EP. 3 Selecting Between the Currently Available CAR-T Therapies for R/R MM: Patient Considerations and Criteria

EP. 4 University of Kansas Medical Center Insights: CAR T Referral Process

EP. 4 University of Kansas Medical Center Insights: CAR T Referral Process

EP. 5 Reviewing CAR T Mechanism & Treatment Process

EP. 5 Reviewing CAR T Mechanism & Treatment Process

EP. 6 Approaches to Bridging Therapy During the CAR T Manufacturing Process

EP. 6 Approaches to Bridging Therapy During the CAR T Manufacturing Process

EP. 7 Comanaging Cases of RR/MM in Patients Receiving CAR T

EP. 7 Comanaging Cases of RR/MM in Patients Receiving CAR T

EP. 8 On-going Clinical Trials With CAR T Therapy in Earlier-Line Multiple Myeloma Treatment: Future Perspectives

EP. 8 On-going Clinical Trials With CAR T Therapy in Earlier-Line Multiple Myeloma Treatment: Future Perspectives

EP. 9 Expert Insights: 68yM High-Risk R/R MM Post HSCT With Progressive Disease—Next Steps?

EP. 9 Expert Insights: 68yM High-Risk R/R MM Post HSCT With Progressive Disease—Next Steps?

EP. 10 Expert Insights: Key Takeaways & Clinical Pearls on CAR T Therapy in R/R MM

EP. 10 Expert Insights: Key Takeaways & Clinical Pearls on CAR T Therapy in R/R MM

Video content above is prompted by the following:

Can you explain your institution’s approach to bridging therapy for patients awaiting CAR T-cell manufacturing and infusion?

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