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Opinion|Videos|February 27, 2026

US Real World CAR-T Patterns in R/R LBCL (ASH 2025 Updates from ABC Consortium)

Author(s)Tara M. Graff, DO, MS, Elizabeth Budde, MD PhD, Alex Herrera, MD

Panelists discuss real-world data from the US ABC Consortium evaluating axicabtagene ciloleucel, tisagenlecleucel, and lisocabtagene maraleucel in relapsed/refractory LBCL. Faculty discuss key differences in manufacturing, review outcomes, and consider toxicity profiles for each of the CAR T products in clinical practice.

Episodes in this series

7 experts are featured in this series.

EP. 1 Key Perspectives on Real World CAR-T Use in R/R LBCL (DESCAR-T & REALYSA Registries)

7 experts are featured in this series.

EP. 2 Examining CAR-T Outcomes in 2L LBCL Treatment (Axi-cel & Liso-cel, DESCAR-T Registry)

7 experts are featured in this series.

EP. 3 US Real World CAR-T Patterns in R/R LBCL (ASH 2025 Updates from ABC Consortium)

7 experts are featured in this series.

EP. 4 Debate Round 1: Treatment selection in biologically aggressive DLBCL

Panelists discuss real-world data from the US ABC Consortium evaluating axicabtageneciloleucel, tisagenlecleucel, and lisocabtagenemaraleucel in relapsed/refractory LBCL. Faculty discuss key differences in manufacturing, review outcomes, and consider toxicity profiles for each of the CAR T products in clinical practice.

Newsletter

Stay up to date on recent advances in the multidisciplinary approach to cancer.

Related Content

7 experts are featured in this series.

Debate Round 1: Treatment selection in biologically aggressive DLBCL

ByTara M. Graff, DO, MS,Elizabeth Budde, MD PhD,Alex Herrera, MD,Geoffrey Shouse, DO, PhD ,Abhinav Deol, MD,Olalekan Oluwole, MD MPH,Nirav Niranjan Shah, MD

February 27th 2026

3 experts are featured in this series

Managing Toxicity Expectations and Sequencing Considerations for CAR T-Cell Therapy in Multiple Myeloma

ByKrina Patel, MD, MSc ,Noopur Raje, MD,Gurbakhash Kaur, MD

February 27th 2026

3 experts are featured in this series

Assessing CAR T-Cell Eligibility and Early Referral Decisions in Relapsed Multiple Myeloma

ByKrina Patel, MD, MSc ,Noopur Raje, MD,Gurbakhash Kaur, MD

February 27th 2026

Redefining Frontline Therapy in Undifferentiated Pleomorphic Sarcoma

BySeth M. Pollack, MD

Published: February 20th 2026 | Updated: February 24th 2026

7 experts are featured in this series.

Examining CAR-T Outcomes in 2L LBCL Treatment (Axi-cel & Liso-cel, DESCAR-T Registry)

ByTara M. Graff, DO, MS,Elizabeth Budde, MD PhD,Alex Herrera, MD,Geoffrey Shouse, DO, PhD ,Abhinav Deol, MD,Olalekan Oluwole, MD MPH,Nirav Niranjan Shah, MD

February 20th 2026

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