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Opinion|Videos|February 20, 2026

Examining CAR-T Outcomes in 2L LBCL Treatment (Axi-cel & Liso-cel, DESCAR-T Registry)

Author(s)Tara M. Graff, DO, MS, Elizabeth Budde, MD PhD, Alex Herrera, MD

Panelists analyze comparative real-world data from the French DESCAR-T registry evaluating axicabtagene ciloleucel and lisocabtagene maraleucel in second-line relapsed/refractory LBCL. Faculty consider distinctions in toxicity profiles along with selection bias, vein-to-vein time, patient frailty, and whether certain patients may preferentially benefit from one CAR T product over another in routine second-line practice.

Episodes in this series

7 experts are featured in this series.

EP. 1 Key Perspectives on Real World CAR-T Use in R/R LBCL (DESCAR-T & REALYSA Registries)

7 experts are featured in this series.

EP. 2 Examining CAR-T Outcomes in 2L LBCL Treatment (Axi-cel & Liso-cel, DESCAR-T Registry)

Panelists analyze comparative real-world data from the French DESCAR-T registry evaluating axicabtageneciloleucel and lisocabtagenemaraleucel in second-line relapsed/refractory LBCL. Faculty consider distinctions in toxicity profiles along with selection bias, vein-to-vein time, patient frailty, and whether certain patients may preferentially benefit from one CAR T product over another in routine second-line practice.

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