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News|Videos|November 7, 2023

Bispecific Therapies in RRMM: Teclistamab, Talquetamab, and Elranatamab Updates

Author(s)Sagar Lonial, MD, FACP, Luciano Costa, MD, PhD, Cesar Rodriguez, MD

Insight into the latest updates on three approved bispecific therapies in the context of relapsed and refractory multiple myeloma, including teclistamab, talquetamab, and elranatamab, discussing response rates, administration, and side effects.

Episodes in this series

Experts on multiple myeloma

EP. 1 Evolving Treatment Paradigms in Relapsed/Refractory Multiple Myeloma

Experts on multiple myeloma

EP. 2 Earlier Use of Novel Therapeutics in Multiple Myeloma Treatment Pathways

Experts on MM

EP. 3 Patient Scenario: Management of Multiple Myeloma With Talquetamab Therapy

Experts on MM

EP. 4 Bispecific Therapies in RRMM: Teclistamab, Talquetamab, and Elranatamab Updates

Experts on MM

EP. 5 Bispecific Therapies in Multiple Myeloma: Impact on Real-World Practice

Experts on MM

EP. 6 Adverse Events With Bispecific Therapy: Dysgeusia, Skin, and Nail Changes

Experts on MM

EP. 7 Managing AEs in Multiple Myeloma: Dosing and Prophylactic Strategies

EP. 8 Multiple Myeloma: Optimizing ICANS and CRS Management

EP. 8 Multiple Myeloma: Optimizing ICANS and CRS Management

$A panel of experts discusses the management of adverse effects including dysgeusia and infections among patients who received bispecific therapies for relapsed/refractory multiple myeloma in the context of a clinical case.$

EP. 9 Managing Toxicity Following Bispecific Therapy in R/R Multiple Myeloma

Experts on MM

EP. 10 Patient Scenario: Navigating Sequencing in Multiple Myeloma

Experts on MM

EP. 11 CAR-T vs BCMA Bispecifics: Navigating Myeloma Treatment Decisions

Experts on MM

EP. 12 Navigating CAR-T Therapy in RRMM: Patient Counsel and Managing AEs

EP. 13 Advancements in Multiple Myeloma IO Therapy: Key Takeaways

EP. 13 Advancements in Multiple Myeloma IO Therapy: Key Takeaways

Newsletter

Stay up to date on recent advances in the multidisciplinary approach to cancer.

Related Content

$Of the 4 patients with relapsed/refractory multiple myeloma who received KLN-1010, 1 complete response and 3 partial responses were achieved at varying levels of MRD sensitivity.$

Investigational BCMA CAR-T Yields Responses/Safety in R/R Multiple Myeloma

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Phase 2 data support further evaluation of frontline BCMA/CD3 bispecific antibody combinations in phase 3 trials.

Teclistamab Combo Elicits Enduring Responses in Transplant-Ineligible NDMM

ByCourtney Flaherty

December 9th 2025

Based on its mechanism of action, anito-cel may cause fewer instances of cytokine release syndrome and delayed toxicities vs other therapies.

Anito-cel May Have Efficient Mechanism in R/R Multiple Myeloma Treatment

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$After a median follow-up of 3.9 months, AZD0120 elicited an overall response rate of 96% among 23 patients with relapsed/refractory multiple myeloma.$

AZD0120 Displays Early Responses/Manageable Safety in R/R Multiple Myeloma

December 9th 2025

Linvoseltamab monotherapy achieved minimal residual disease negativity in 95% of patients with newly diagnosed multiple myeloma.

Linvoseltamab Yields High Response in Newly Diagnosed Multiple Myeloma

BySabrina Serani

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